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台湾加护病房接受机械通气的老年患者中“不进行心肺复苏”医嘱的特征。

Characteristics of "do not resuscitate" orders among elderly patients receiving mechanical ventilation in the intensive care unit in Taiwan.

作者信息

Chen Pei-Jun, Ho Chung-Han, Lin Ying-Jia, Chang Ming-Hung, Liao Kuang-Ming

机构信息

Department of Nursing, Nantou Hospital, Ministry of Health and Welfare, Nantou, Taiwan.

Department of Medical Research, Chi Mei Medical Center, Tainan, Taiwan.

出版信息

Front Med (Lausanne). 2024 May 23;11:1373726. doi: 10.3389/fmed.2024.1373726. eCollection 2024.

Abstract

OBJECTIVE

As patient life expectancy has increased and people are living longer than before, the rate of mechanical ventilation among elderly patients in the intensive care unit has increased. Older patients who receive mechanical ventilation and have multiple comorbidities are more likely to have a do not resuscitate order than are younger patients with fewer comorbidities. The aim of our study was to describe the patient characteristics and predictive factors of do not resuscitate orders during hospitalization among elderly patients who received ventilation in the intensive care unit.

METHODS

This was a retrospective review of the electronic medical records of patients in the intensive care unit of a teaching hospital in southern Taiwan. We enrolled patients admitted to the general intensive care unit from January 1, 2018, to September 31, 2020, and patients older than 80 years who experienced respiratory failure, were intubated and received mechanical ventilation. We analyzed patient demographics, disease severity during hospitalization and comorbidities. If a patient had multiple admissions to the intensive care unit, only the first admission was recorded.

RESULTS

Of the 305 patients over 80 years of age with respiratory failure who were intubated and placed on a ventilator, 66 were excluded because of incomplete data, and 13 were excluded because they had already signed a do not resuscitate order prior to admission to the hospital. Ultimately, 226 patients were included in this study. A higher acute physiology and chronic health evaluation II score (>30) was also associated with an increased likelihood of a do not resuscitate order (odds ratio (OR) = 3.85, 95% CI = 1.09-13.62,  = 0.0362). Patients who had acute kidney injury or cerebrovascular accident were more likely to have a do not resuscitate order (OR = 2.74, 95% CI = 1.03-7.28,  = 0.0428 and OR = 7.32, 95% CI = 2.02-26.49,  = 0.0024, respectively).

CONCLUSION

Our study showed that older age, greater disease severity, and certain critical interventions were associated with a greater propensity for do not resuscitate orders, which is crucial for understanding patient preferences and guiding end-of-life care discussions. These findings highlight the importance of clinical severity and specific health events in predicting end-of-life care preferences in older patient groups.

摘要

目的

随着患者预期寿命的增加,人们比以往活得更长,重症监护病房中老年患者的机械通气率有所上升。与合并症较少的年轻患者相比,接受机械通气且合并多种疾病的老年患者更有可能有“不要复苏”医嘱。我们研究的目的是描述在重症监护病房接受通气治疗的老年患者住院期间“不要复苏”医嘱的患者特征和预测因素。

方法

这是一项对台湾南部一家教学医院重症监护病房患者电子病历的回顾性研究。我们纳入了2018年1月1日至2020年9月31日入住综合重症监护病房的患者,以及80岁以上经历呼吸衰竭、插管并接受机械通气的患者。我们分析了患者的人口统计学数据、住院期间的疾病严重程度和合并症。如果患者多次入住重症监护病房,则仅记录首次入院情况。

结果

在305名80岁以上因呼吸衰竭插管并使用呼吸机的患者中,66名因数据不完整被排除,13名因入院前已签署“不要复苏”医嘱被排除。最终,226名患者纳入本研究。较高的急性生理与慢性健康状况评分II(>30)也与“不要复苏”医嘱的可能性增加相关(比值比(OR)=3.85,95%置信区间(CI)=1.09 - 13.62,P = 0.0362)。发生急性肾损伤或脑血管意外的患者更有可能有“不要复苏”医嘱(分别为OR = 2.74,95% CI = 1.03 - 7.28,P = 0.0428和OR = 7.32,95% CI = 2.02 - 26.49,P = 0.0024)。

结论

我们的研究表明,高龄、更高的疾病严重程度和某些关键干预措施与“不要复苏”医嘱的更大倾向相关,这对于理解患者偏好和指导临终关怀讨论至关重要。这些发现凸显了临床严重程度和特定健康事件在预测老年患者群体临终关怀偏好方面的重要性。

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