Toader Corneliu, Arsene Dorel, Popa Andrei Adrian, Covache-Busuioc Razvan-Adrian, Bratu Bogdan-Gabriel, Glavan Luca-Andrei, Dumitrascu David-Ioan, Ciurea Alexandru Vladimir
Department of Neurosurgery, "Carol Davila" University of Medicine and Pharmacy, Bucharest, ROU.
Department of Anatomical Pathology, "Carol Davila" University of Medicine and Pharmacy, Bucharest, ROU.
Cureus. 2024 May 7;16(5):e59798. doi: 10.7759/cureus.59798. eCollection 2024 May.
Solitary fibrous tumor (SFT) is a rare type of tumor characterized by spindle-shaped cells originating from mesenchymal tissue. This case series presents a collection of 14 intracranial solitary fibrous tumors treated between 2014 and 2022 in our institute in Bucharest, Romania. Through a systematic investigation, key aspects spanning the preoperative, intraoperative, and postoperative phases of patient care were highlighted. Our study examines various factors including tumor location (which was very heterogeneous), size (median of 49 mm, ranging between 22 mm and 70 mm), surgical techniques employed, and recurrence rates. The data was analyzed using Python version 3.10 (Python Software Foundation, Wilmington, Delaware, United States). Gender disparities in SFT were noted, particularly the male-to-female ratio which was 5:9. The use of the Medical Research Council (MRC) Scale for Muscle Strength aided in evaluating severity and postoperative outcomes. GTR was achieved in nine out of 14 cases (64.28%), prolonging the period of recurrence-free survival.
孤立性纤维瘤(SFT)是一种罕见的肿瘤类型,其特征是起源于间叶组织的梭形细胞。本病例系列展示了2014年至2022年期间在罗马尼亚布加勒斯特我们研究所治疗的14例颅内孤立性纤维瘤。通过系统调查,突出了患者护理术前、术中和术后阶段的关键方面。我们的研究考察了各种因素,包括肿瘤位置(非常不均匀)、大小(中位数为49毫米,范围在22毫米至70毫米之间)、采用的手术技术以及复发率。使用Python 3.10版本(Python软件基金会,美国特拉华州威尔明顿)对数据进行了分析。注意到SFT存在性别差异,尤其是男女比例为5:9。使用医学研究委员会(MRC)肌肉力量量表有助于评估严重程度和术后结果。14例中有9例(64.28%)实现了全切除,延长了无复发生存期。