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累及肺动脉瓣的黏液瘤——一例非典型心脏肿瘤的病例报告,采用非常规方法治疗。

Myxoma Involving the Pulmonary Valve - A Case Report of an Atypical Cardiac Tumor, Treated Using an Unusual Approach.

作者信息

Bhagia Geeta, Hussain Nasir, Arty Fnu, Chakravarthy Mithun, Shah Moneal

机构信息

Rochester General Hospital, Rochester, USA.

UHS Wilson Medical Center, Johnson City, USA.

出版信息

Eur J Case Rep Intern Med. 2024 May 22;11(6):004519. doi: 10.12890/2024_004519. eCollection 2024.

DOI:10.12890/2024_004519
PMID:38846647
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11152223/
Abstract

BACKGROUND

Atypical myxoma has been reported in various locations in the heart, however, myxoma involving the pulmonary valve is rare. Here we present a case of pulmonic valve myxoma which was resected via a percutaneous approach.

CASE REPORT

A 66-year-old female with known metastatic adenocarcinoma of the lung, and chronic obstructive pulmonary disease presented with acute onset shortness of breath for two days. The patient experienced respiratory arrest en-route to the hospital and required intubation. Computed tomography angiography (CTA) of the chest revealed a new 1.4 × 1.6 cm intracardiac mass along the pulmonary valve. Further evaluation with cardiac magnetic resonance imaging revealed it to be a large vascular tumor on the ventricular side of the pulmonary valve, attached with a narrow stalk. Due to high surgical risk, the patient underwent transesophageal echocardiographic guided percutaneous removal of the mass. Pathology confirmed the mass to be a myxoma.

CONCLUSION

Atypical myxoma should be considered in the differential diagnosis of valvular masses. Percutaneous resection of valvular masses may be feasible in high-risk surgical patients.

LEARNING POINTS

Pulmonary valve myxoma is a rare condition and the literature on the characteristics and treatment options for pulmonary valve myxoma is limited.Our patient was treated with a minimally invasive treatment approach: removal of a tumor with intra operative transesophageal echocardiographic guidance using AngioVac and Flow Triever catheters.Percutaneous resection of valvular masses may be feasible in high surgical risk patients.

摘要

背景

非典型黏液瘤已在心脏的各个部位被报道,然而,累及肺动脉瓣的黏液瘤罕见。在此,我们报告一例经皮途径切除的肺动脉瓣黏液瘤病例。

病例报告

一名66岁女性,已知患有肺转移性腺癌和慢性阻塞性肺疾病,因急性发作气短两天就诊。患者在前往医院途中发生呼吸骤停,需要插管。胸部计算机断层扫描血管造影(CTA)显示沿肺动脉瓣有一个新的1.4×1.6 cm心内肿块。心脏磁共振成像进一步评估显示,它是一个位于肺动脉瓣心室侧的大型血管肿瘤,附着有一个狭窄的蒂。由于手术风险高,患者接受了经食管超声心动图引导下经皮切除肿块。病理证实肿块为黏液瘤。

结论

在瓣膜肿块的鉴别诊断中应考虑非典型黏液瘤。对于手术风险高的患者,经皮切除瓣膜肿块可能是可行的。

学习要点

肺动脉瓣黏液瘤是一种罕见疾病,关于肺动脉瓣黏液瘤的特征和治疗选择的文献有限。我们的患者采用了微创治疗方法:使用AngioVac和Flow Triever导管在术中经食管超声心动图引导下切除肿瘤。对于手术风险高的患者,经皮切除瓣膜肿块可能是可行的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fbf/11152223/e16d209a66b8/4519_Fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fbf/11152223/3fafdde10344/4519_Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fbf/11152223/d2f04d19212e/4519_Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fbf/11152223/af24beeb3c42/4519_Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fbf/11152223/b749b76880ee/4519_Fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fbf/11152223/e16d209a66b8/4519_Fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fbf/11152223/3fafdde10344/4519_Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fbf/11152223/d2f04d19212e/4519_Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fbf/11152223/af24beeb3c42/4519_Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fbf/11152223/b749b76880ee/4519_Fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fbf/11152223/e16d209a66b8/4519_Fig5.jpg

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本文引用的文献

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The Simplified Extraction of Atrial Tumor With Targeted Loop Electricity (SEATTLE) Procedure.采用靶向环形电隔离术的心房肿瘤简易切除术(SEATTLE 手术)
JACC Case Rep. 2023 Mar 15;10:101758. doi: 10.1016/j.jaccas.2023.101758.
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Pulmonary valve myxoma requiring pulmonary valve replacement: a case report.需要进行肺动脉瓣置换术的肺动脉瓣黏液瘤:一例报告
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Cardiac Myxoma: Review and Update of Contemporary Immunohistochemical Markers and Molecular Pathology.心脏黏液瘤:当代免疫组织化学标志物和分子病理学的回顾与更新。
Adv Anat Pathol. 2020 Nov;27(6):380-384. doi: 10.1097/PAP.0000000000000275.
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Tricuspid valve obstruction and right heart failure due to a giant right atrial myxoma arising from the superior vena cava.源于上腔静脉的巨大右房黏液瘤导致三尖瓣梗阻及右心衰竭。
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Surgical excision of cardiac myxomas: twenty years experience at a single institution.心脏黏液瘤的外科切除:单中心 20 年经验。
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