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假性剥脱综合征的流行病学

The epidemiology of the pseudo-exfoliation syndrome.

作者信息

Dell W M

出版信息

J Am Optom Assoc. 1985 Feb;56(2):113-9.

PMID:3884692
Abstract

The pseudo-exfoliation syndrome is characterized by the deposition of light gray or white dandruff-like flakes on various intraocular structures, most clinically apparent on the anterior lens capsule and pupillary margin but more significantly on the trabecular meshwork and ciliary processes. Its prevalence in various populations and relationship to age, sex, geography, heredity, and particularly to glaucoma have been the subject of numerous studies. Its prevalence is generally variable (depending on the subject population) and ranges from 1 to 8 percent, increasing with age. It is positively associated with higher levels of intraocular pressure and open-angle glaucoma. Although further carefully-controlled studies of prevalence and their relationship with glaucoma are desirable, patients with evidence of pseudo-exfoliation should be treated as glaucoma suspects.

摘要

假性剥脱综合征的特征是在各种眼内结构上沉积浅灰色或白色头皮屑样薄片,在临床上最明显见于晶状体前囊和瞳孔边缘,但在小梁网和睫状体上更为显著。其在不同人群中的患病率以及与年龄、性别、地理、遗传,尤其是与青光眼的关系一直是众多研究的主题。其患病率通常各不相同(取决于研究对象群体),范围为1%至8%,并随年龄增长而增加。它与较高的眼压和开角型青光眼呈正相关。尽管需要进一步对患病率及其与青光眼的关系进行严格控制的研究,但有假性剥脱证据的患者应被视为青光眼疑似患者。

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引用本文的文献

1
Pseudoexfoliation syndrome at a Singapore eye clinic.新加坡一家眼科诊所的假性剥脱综合征
Clin Ophthalmol. 2015 Sep 3;9:1619-24. doi: 10.2147/OPTH.S87155. eCollection 2015.
2
Exfoliation syndrome and occludable angles.剥脱综合征与可闭角
Trans Am Ophthalmol Soc. 1994;92:845-944.