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SSRI 导致的胎儿导管狭窄:病例报告。

Fetal ductal constriction caused by SSRI: A case report.

机构信息

MC Markovs, Sofia, Bulgaria.

High-Risk Pregnancy Clinic, University Hospital of Obstetrics and Gynecology Maichin Dom, Sofia, Bulgaria.

出版信息

J Clin Ultrasound. 2024 Oct;52(8):1179-1182. doi: 10.1002/jcu.23740. Epub 2024 Jun 7.

DOI:10.1002/jcu.23740
PMID:38847485
Abstract

A 31-week fetus was diagnosed with premature ductal constriction due to maternal treatment with sertraline. An emergent Cesarean section was performed at 32 gestational weeks. The baby was born in a severely depressed condition, with supra-systemic pulmonary hypertension, requiring intubation, mechanical ventilation, and milrinone infusion. The patient's condition improved rapidly, allowing weaning from the ventilator and the inodilator therapy. The baby was discharged home at 38 weeks postmenstrual age, in good general condition, without any signs of pulmonary hypertension, requiring no respiratory support. The echo examinations on the first and third months after birth were normal.

摘要

一名 31 周的胎儿因母亲接受舍曲林治疗而被诊断为早产的动脉导管狭窄。在 32 孕周时进行了紧急剖宫产。婴儿出生时情况严重,患有系统性肺动脉高压,需要插管、机械通气和米力农输注。患者的病情迅速改善,呼吸机和正性肌力药物治疗逐渐撤机。婴儿在孕龄 38 周时出院,一般情况良好,无肺动脉高压迹象,无需呼吸支持。出生后第一个和第三个月的超声心动图检查正常。

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