Angiology & Vascular Surgery Department. Unidade Local de Saúde de Santo António. Porto; Health School. Instituto Politécnico de Porto. Porto. Portugal.
Angiology & Vascular Surgery Department. Unidade Local de Saúde de Santo António. Porto. Portugal.
Acta Med Port. 2024 Jun 3;37(6):436-444. doi: 10.20344/amp.20760.
Peripheral arterial disease (PAD) is an occlusive atherosclerotic disease of the arteries of the extremities of the body that affects more than 230 million people worldwide. The most common symptom is intermittent claudication, described as leg pain which occurs mainly while walking. The symptoms impair the ambulation and functional capacity of patients, leading to loss of mobility, disease deterioration, increased risk of other cardiovascular diseases, and lower quality of life (QoL). Therefore, the aim of this study was to perform a cross-cultural adaptation and validation of the VascuQol-6 questionnaire for the Portuguese population to obtain a quick, sensitive, and easy-to-use way to assess the QoL of Portuguese patients diagnosed with PAD.
The Vascular Quality of Life-6 Questionnaire (VascuQoL-6) was adapted and translated into European Portuguese using standard validation methodology, including 115 patients with a mean age of 64.67 (7.23) years, with PAD with IC stable for more than three months; and ABI < 0.9 at rest. VascuQoL-6, SF-36, International Physical Activity Questionnaire (IPAQ), and the PAD Knowledge Questionnaire (PADKQ) were used. Reliability, construct validity analysis through convergent and discriminant validity, known-group validity, and responsiveness analysis were tested.
The Cronbach's alpha was 0.64 and the average inter-item correlation was 0.27, indicating acceptable internal consistency. VascuQoL-6 was positively associated with SF-36 Physical Component Summary and Mental Component Summary scores (r = 0.64, p < 0.01 and r = 0.42, p < 0.01, respectively). In turn, there was no significant correlation between VascuQoL-6 scores and the PADKQ or IPAQ. A statistically significant difference between groups according to IC severity [F(2.47) = 8.35, p < 0.001] was found. A paired samples t-test showed differences between VascuQol-6 scores before a walking program (M = 15.65, SD = 3.09), and after a walking program (M = 17.41, SD = 2.71), t(67) = 3.94, p ≤ 0.001.
The VascuQoL-6 is a six-item instrument to assess the QoL associated with PAD with good psychometric properties, convergent and discriminant validity with SF-36, PADKQ and IPAQ. The instrument proved to have known group validity and responsiveness.
外周动脉疾病（PAD）是一种累及身体四肢动脉的闭塞性动脉粥样硬化性疾病，影响着全球超过 2.3 亿人。最常见的症状是间歇性跛行，表现为主要在行走时发生的腿部疼痛。这些症状会影响患者的活动能力和功能能力，导致活动能力丧失、疾病恶化、增加其他心血管疾病的风险以及降低生活质量（QoL）。因此，本研究旨在对血管质量问卷-6 （VascuQoL-6）进行跨文化适应性和验证，以便为葡萄牙 PAD 患者获得快速、敏感和易于使用的方式来评估其生活质量。
采用标准验证方法将血管质量问卷-6 （VascuQoL-6）改编并翻译成欧洲葡萄牙语，包括 115 名平均年龄为 64.67（7.23）岁、患有 PAD 且跛行稳定超过三个月、静息时踝肱指数（ABI）<0.9 的患者。同时使用了 VascuQoL-6、SF-36、国际体力活动问卷（IPAQ）和 PAD 知识问卷（PADKQ）。对信度、通过收敛和判别有效性分析的结构有效性、已知组有效性和反应性分析进行了测试。
Cronbach's alpha 为 0.64，平均项目间相关性为 0.27，表明内部一致性可接受。VascuQoL-6 与 SF-36 生理成分综合评分和心理成分综合评分呈正相关（r = 0.64，p <0.01 和 r = 0.42，p <0.01）。反过来，VascuQoL-6 评分与 PADKQ 或 IPAQ 之间没有显著相关性。根据 IC 严重程度（F(2.47) = 8.35，p <0.001）发现组间存在统计学差异。配对样本 t 检验显示，步行计划前后（VascuQol-6）评分存在差异（M = 15.65，SD = 3.09），（M = 17.41，SD = 2.71），t(67) = 3.94，p ≤ 0.001。
VascuQoL-6 是一种六条目工具，用于评估与 PAD 相关的生活质量，具有良好的心理测量特性，与 SF-36、PADKQ 和 IPAQ 具有收敛和判别有效性。该工具具有已知组有效性和反应性。
