State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Department of Operative Dentistry and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.
School of Information and Communication Engineering, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
J Endod. 2024 Sep;50(9):1298-1306. doi: 10.1016/j.joen.2024.05.015. Epub 2024 Jun 6.
In dental clinical practice, cone-beam computed tomography (CBCT) is commonly used to assist practitioners to recognize the complex morphology of root canal systems; however, because of its resolution limitations, certain small anatomical structures still cannot be accurately recognized on CBCT. The purpose of this study was to perform image super-resolution (SR) processing on CBCT images of extracted human teeth with the help of a deep learning model, and to compare the differences among CBCT, super-resolution computed tomography (SRCT), and micro-computed tomography (Micro-CT) images through three-dimensional reconstruction.
The deep learning model (Basicvsr++) was selected and modified. The dataset consisted of 171 extracted teeth that met inclusion criteria, with 40 maxillary first molars as the training set and 40 maxillary first molars as well as 91 teeth from other tooth positions as the external test set. The corresponding CBCT, SRCT, and Micro-CT images of each tooth in test sets were reconstructed using Mimics Research 17.0, and the root canal recognition rates in the 3 groups were recorded. The following parameters were measured: volume of hard tissue (V1), volume of pulp chamber and root canal system (V2), length of visible root canals under orifice (VL-X, where X represents the specific root canal), and intersection angle between coronal axis of canal and long axis of tooth (∠X, where X represents the specific root canal). Data were statistically analyzed between CBCT and SRCT images using paired sample t-test and Wilcoxon test analysis, with the measurement from Micro-CT images as the gold standard.
Images from all tested teeth were successfully processed with the SR program. In 4-canal maxillary first molar, identification of MB2 was 72% (18/25) in CBCT group, 92% (23/25) in SRCT group, and 100% (25/25) in Micro-CT group. The difference of hard tissue volume between SRCT and Micro-CT was significantly smaller than that between CBCT and Micro-CT in all tested teeth except 4-canal mandibular first molar (P < .05). Similar results were obtained in volume of pulp chamber and root canal system in all tested teeth (P < .05). As for length of visible root canals under orifice, the difference between SRCT and Micro-CT was significantly smaller than that between CBCT and Micro-CT (P < .05) in most root canals.
The deep learning model developed in this study helps to optimize the root canal morphology of extracted teeth in CBCT. And it may be helpful for the identification of MB2 in the maxillary first molar.
在牙科临床实践中,锥形束计算机断层扫描(CBCT)常用于帮助医生识别根管系统的复杂形态;但由于其分辨率的限制,某些小的解剖结构仍无法在 CBCT 上准确识别。本研究旨在借助深度学习模型对离体人牙的 CBCT 图像进行超分辨率(SR)处理,并通过三维重建比较 CBCT、SRCT 和微计算机断层扫描(Micro-CT)图像的差异。
选择并修改深度学习模型(Basicvsr++)。数据集由 171 颗符合纳入标准的离体牙组成,其中 40 颗上颌第一磨牙作为训练集,40 颗上颌第一磨牙和 91 颗其他牙位的牙齿作为外部测试集。使用 Mimics Research 17.0 对每个测试集牙齿的相应 CBCT、SRCT 和 Micro-CT 图像进行重建,并记录 3 组的根管识别率。测量以下参数:硬组织体积(V1)、牙髓腔和根管系统体积(V2)、根管口下可见根管长度(VL-X,其中 X 代表特定根管)和根管冠轴与牙长轴的夹角(∠X,其中 X 代表特定根管)。使用配对样本 t 检验和 Wilcoxon 检验分析 CBCT 和 SRCT 图像之间的数据,以 Micro-CT 图像的测量值为金标准。
所有测试牙的图像均成功用 SR 程序处理。在上颌第一磨牙 4 根管中,CBCT 组 MB2 的识别率为 72%(18/25),SRCT 组为 92%(23/25),Micro-CT 组为 100%(25/25)。除 4 根管下颌第一磨牙外,所有测试牙的硬组织体积差异在 SRCT 和 Micro-CT 之间明显小于 CBCT 和 Micro-CT 之间(P<0.05)。所有测试牙的牙髓腔和根管系统体积差异也均如此(P<0.05)。至于根管口下可见根管长度,大多数根管中 SRCT 和 Micro-CT 之间的差异明显小于 CBCT 和 Micro-CT 之间的差异(P<0.05)。
本研究开发的深度学习模型有助于优化 CBCT 中离体牙的根管形态。并且它可能有助于上颌第一磨牙 MB2 的识别。