Department of Surgical Intensive Care Unit, Children's Hospital of Nanjing Medical University, No.72 Guangzhou Road, Nanjing, Jiangsu Province, 210008, China.
BMC Pediatr. 2024 Jun 8;24(1):387. doi: 10.1186/s12887-024-04866-0.
Necrotizing enterocolitis (NEC) and intracranial hemorrhage are severe emergencies in the neonatal period. The two do not appear to be correlated. However, our report suggests that parenchymal brain hemorrhage in full-term newborns may put patients at risk for NEC by altering intestinal function through the brain-gut axis.
We present a case of spontaneous parenchymal cerebral hemorrhage in a full-term newborn who developed early-stage NEC on Day 15.
It is possible to consider brain parenchymal hemorrhage as a risk factor for the appearance of NEC. Clinicians should be highly cautious about NEC in infants who have experienced parenchymal hemorrhage. This article is the first to discuss the relationship between parenchymal hemorrhage and NEC in full-term newborns.
坏死性小肠结肠炎(NEC)和颅内出血是新生儿期的严重急症。两者似乎没有关联。然而,我们的报告表明,足月新生儿的实质脑内出血可能通过脑-肠轴改变肠道功能,使患者面临 NEC 的风险。
我们报告了一例足月新生儿自发性实质脑内出血,该患儿在第 15 天出现早期 NEC。
可以将脑实质出血视为 NEC 出现的一个危险因素。经历过实质出血的婴儿,临床医生应该高度警惕 NEC 的发生。本文首次讨论了足月新生儿实质出血与 NEC 之间的关系。