Department of Large Animal Medicine, University of Georgia College of Veterinary Medicine, 2200 College Station Road, Athens, GA 30602, USA.
Department of Large Animal Medicine, University of Georgia College of Veterinary Medicine, 2200 College Station Road, Athens, GA 30602, USA.
Vet Clin North Am Equine Pract. 2024 Aug;40(2):307-339. doi: 10.1016/j.cveq.2024.04.007. Epub 2024 Jun 8.
Immunomodulators can stimulate, suppress, or regulate one or many aspects of the immune response. Use of a variety of immunostimulants, immunosuppressors, and anti-inflammatory drugs are described in horses, but the evidence supporting their efficacy is variable. Corticosteroids and nonsteroidal anti-inflammatory drugs are the best characterized immunomodulators in horses, but further study is needed to fully define their ideal dosing protocols and indications and to characterize the efficacy of other immunomodulators in equine medicine.
免疫调节剂可以刺激、抑制或调节免疫反应的一个或多个方面。在马中描述了各种免疫刺激剂、免疫抑制剂和抗炎药物的使用,但支持它们疗效的证据是可变的。皮质类固醇和非甾体抗炎药是马中最具特征的免疫调节剂,但需要进一步研究来充分定义它们的理想剂量方案和适应症,并确定其他免疫调节剂在马医学中的疗效。