Wink Jason D, Rhemtulla Irfan A, Fix William, Enriquez Fabiola, Mauch Jaclyn, Barbieri John, Miller Christopher J, Chang Benjamin, Lin Ines C, Kovach Stephen J
Division of Plastic Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, United States.
Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania, United States.
J Hand Microsurg. 2024 Apr 16;16(1):100001. doi: 10.1055/s-0040-1714649. eCollection 2024 Mar.
Mohs surgery and reconstruction has enabled tissue-preserving resection of cutaneous malignancies. The goal of our case series evaluation is to present reconstructive techniques and functional outcomes in patients undergoing digit-sparing treatment for primary melanoma.
A chart review was performed to identify consecutive patients undergoing Mohs surgery and reconstruction for melanoma of the digits. Quality of life (QOL) survey was performed to assess function after the procedure.
Thirty-two patients (13 hand, 19 foot, Age: 65.03 +/-17.78 years) who were undergoing Mohs surgery were identified. No recurrence was identified with an average follow-up of 16.1 months (1-95 months). The average defect size was 5.79 +/-4.54 cm. Reconstruction was performed 0-4 days after resection. The most common techniques included full-thickness skin graft (FTSG) ( = 7), collagen matrix + FTSG ( = 4), and volar advancement flap ( = 7). The reconstructive technique choice appears correlated with defect size ( = 0.0125). Neuro-QOL upper extremity survey results showed a difference that approached statistical significance between patients who underwent digit-sparing treatment ( = 7) versus direct to amputation controls ( = 5) ( = 0.072). No survey differences between digit-sparing treatment ( = 10) and amputation ( = 8) were identified in the lower extremity ( = 0.61).
Our results show digit-sparing treatment can confirm clear surgical margins and a trend toward improvement in upper extremity function compared with immediate amputation.
莫氏手术及重建技术能够对皮肤恶性肿瘤进行保留组织的切除。我们本病例系列评估的目的是展示接受保留手指治疗原发性黑色素瘤患者的重建技术及功能结果。
进行一项图表回顾,以确定连续接受莫氏手术及手指黑色素瘤重建手术的患者。进行生活质量(QOL)调查以评估术后功能。
共确定32例接受莫氏手术的患者(13例手部,19例足部;年龄:65.03±17.78岁)。平均随访16.1个月(1 - 95个月),未发现复发情况。平均缺损大小为5.79±4.54平方厘米。切除术后0 - 4天进行重建。最常用的技术包括全厚皮片移植(FTSG)(n = 7)、胶原基质 + FTSG(n = 4)和掌侧推进皮瓣(n = 7)。重建技术的选择似乎与缺损大小相关(p = 0.0125)。上肢神经生活质量调查结果显示,接受保留手指治疗的患者(n = 7)与直接截肢对照组(n = 5)之间的差异接近统计学意义(p = 0.072)。在下肢,保留手指治疗组(n = 10)和截肢组(n = 8)之间未发现调查差异(p = 0.61)。
我们的结果表明,与立即截肢相比,保留手指治疗能够确保手术切缘清晰,且上肢功能有改善的趋势。