Division of Plastic Surgery, University of Kentucky College of Medicine, 740 S. Limestone Street, Lexington, KY 40536, USA.
Healthcare (Basel). 2014 Mar 6;2(1):125-38. doi: 10.3390/healthcare2010125.
Melanoma of the hand represents a complicated clinical entity. Anatomic features of the hand create challenges in successful management of melanoma not encountered elsewhere in the body. The objectives of this article are to outline current standards for managing melanoma of the hand including diagnosis, surgical, and chemotherapeutic management. Particular emphasis will be placed on currently debated topics of the role of sentinel lymph node biopsy, the role of Mohs micrographic surgery, tissue sparing management of subungual melanoma, and the consideration of melanoma of the hand as a distinct entity based on clinical and molecular studies.
手部黑色素瘤是一种复杂的临床实体。手部的解剖结构特征给黑色素瘤的成功治疗带来了挑战，这些挑战在身体其他部位并不常见。本文的目的是概述手部黑色素瘤的当前治疗标准，包括诊断、手术和化疗管理。特别强调目前有争议的话题，如前哨淋巴结活检的作用、Mohs 显微外科手术的作用、甲下黑色素瘤的保组织治疗以及根据临床和分子研究将手部黑色素瘤视为一种独特实体的考虑。
