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综合消肿治疗对乳腺癌相关淋巴水肿女性的衰弱及生活质量的影响:治疗前后研究

Effect of complex decongestive therapy on frailty and quality of life in women with breast cancer-related lymphedema: the before-and-after treatment study.

作者信息

Kavak Songül Keskin, Ünver Gamze

机构信息

Physical Therapy and Rehabilitation Clinic, Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, Ankara, Türkiye.

Nursing Department, Faculty of Health Science, Kutahya Health Sciences University, Kutahya, Türkiye.

出版信息

Front Oncol. 2024 May 24;14:1297074. doi: 10.3389/fonc.2024.1297074. eCollection 2024.

Abstract

OBJECTIVE

To investigate the impact of Complex Decongestive Therapy (CDT) on the severity of frailty and quality of life in individuals suffering from postmastectomy lymphedema syndrome.

METHODS

Participants who met the inclusion criteria were informed about CDT and informed consent was obtained. Edmonton Frailty Scale (EFS), extremity volüme (EV), lymphedema stage(LS), EQ-5D General Quality of Life Scale (EQ-5D-5L), and Quick Disabilities of Arm, Shoulder, and Hand (DASH) scores were evaluated by the same physician before and after treatment. A total of 15 sessions of CDT were performed for 3 weeks, five days a week. During the treatment period, hospitalized patients received guidance from a nurse on protecting the affected arm in their daily routine.

RESULTS

Eighty patients with breast cancer-related lymphedema who met the inclusion criteria were included in the study. Following a period of 3 weeks of practice and training, the specialist physician conducted the final evaluation and assessments. All patients showed a statistically significant reduction in EV, and regression in LS, EFS, and Quick DASH score (p<0.001). Statistically significant improvement was also observed in quality of life and general health status. (p<0.001).

CONCLUSION

The application of 15 sessions of CDT and educational interventions to women with postmastectomy lymphedema syndrome due to breast cancer yielded positive outcomes. This approach led to an enhancement in patients' functional capacity, improving their quality of life and a subsequent reduction in the severity of frailty.

摘要

目的

探讨综合消肿治疗(CDT)对乳腺癌术后淋巴水肿综合征患者衰弱严重程度及生活质量的影响。

方法

符合纳入标准的参与者被告知CDT相关信息并获得知情同意。由同一位医生在治疗前后评估埃德蒙顿衰弱量表(EFS)、肢体体积(EV)、淋巴水肿分期(LS)、EQ-5D生活质量综合量表(EQ-5D-5L)以及手臂、肩部和手部快速残疾评定量表(DASH)评分。共进行3周、每周5天、总计15次的CDT治疗。治疗期间,住院患者在日常生活中接受护士关于保护患侧手臂的指导。

结果

80例符合纳入标准的乳腺癌相关淋巴水肿患者纳入本研究。经过3周的实践和训练后,专科医生进行了最终评估。所有患者的EV均有统计学意义的降低,LS、EFS和快速DASH评分均有所改善(p<0.001)。生活质量和总体健康状况也有统计学意义的改善(p<0.001)。

结论

对因乳腺癌导致乳腺癌术后淋巴水肿综合征的女性应用15次CDT及教育干预产生了积极效果。这种方法提高了患者的功能能力,改善了他们的生活质量,并随后降低了衰弱的严重程度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe7a/11157059/8288da43e5bc/fonc-14-1297074-g001.jpg

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