口腔扁平苔藓和口腔黏膜下纤维化的CD34免疫组织化学评估
Immuno-histochemical evaluation of CD34 for OLP and OSMF.
作者信息
Shrivastava Harshit, Shenoy Mahesh, Sayed Abdul Nishath, Pramod Gujjar Deepashree, Shahi Ajoy Kumar, Dhir Preeti, Patel Bhumika J, Makkad Ramanpal Sing
机构信息
Department of Oral and Maxillofacial Surgery, Hitkarini Dental College and Hospital, Jabalpur, Madhya Pradesh., India.
Department of OMFS & Diagnostic Sciences, College of Medicine & Dentistry, Riyadh Elm University, P.O. Box 84891 - Riyadh 11681, Kingdom of Saudi Arabia.
出版信息
Bioinformation. 2024 Apr 30;20(4):358-361. doi: 10.6026/973206300200358. eCollection 2024.
Immuno-histochemical evaluation of CD34 in oral lichen planus (OLP) and Oral Submucous Fibrosis (OSMF) is of interest to dentist.20 specimens of normal oral mucosa (buccal mucosa/gingiva tissue) from patients who had extractions performed as part of orthodontic treatment comprised Group I, the control group. Group II comprised 30 individuals with a diagnosis of oral lichen planus. 30 OSMF cases with diagnoses is Group III. These 80 specimens were all given consideration when choosing for CD34immuno-histochemical staining. The CD34 was greater in all categories of OLP and OSMF when compared to normal controls. Maximum CD34 expression was observed in erosive OLP (147.41±17.60) followed by OSMF (116.01 ±11.72) and reticular OLP (105.01±11.62). Data was statistically significant (p<0.001).Immunohistochemistry of CD34 evaluation is a potential diagnostic marker for OLP and OSMF.
口腔扁平苔藓（OLP）和口腔黏膜下纤维化（OSMF）中CD34的免疫组织化学评估受到牙医的关注。作为正畸治疗一部分而接受拔牙的患者的20份正常口腔黏膜（颊黏膜/牙龈组织）标本组成了I组，即对照组。II组由30例诊断为口腔扁平苔藓的个体组成。III组为30例诊断为口腔黏膜下纤维化的病例。在选择进行CD34免疫组织化学染色时，对这80份标本都进行了考虑。与正常对照组相比，所有类型的OLP和OSMF中的CD34均更高。在糜烂性OLP（147.41±17.60）中观察到最高的CD34表达，其次是OSMF（116.01±11.72）和网状OLP（105.01±11.62）。数据具有统计学意义（p<0.001）。CD34评估的免疫组织化学是OLP和OSMF的一种潜在诊断标志物。
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