二维平面成像与三维单光子发射计算机断层扫描成像在钇-90放射性栓塞治疗中肺分流分数计算差异的影响
Implications of lung shunt fraction calculation discrepancy in Yttrium-90 radioembolization treatment from 2D planar vs 3D single photon emission CT imaging.
作者信息
Gamero Kubota Paula, Molvar Christopher, Wagner Robert, Allam Emad, Halama James, James Judy R
机构信息
Department of Radiology and Medical Imaging, Loyola University School of Medicine, Maywood, IL60153, United States.
出版信息
BJR Case Rep. 2024 May 28;10(3):uaae016. doi: 10.1093/bjrcr/uaae016. eCollection 2024 May.
Abstract
The safety and efficacy of Yttrium-90 (Y-90) radio-embolization therapy is partly dependent on the lung shunt fraction (LSF). There may be a notable disparity between LSF when calculated using 2D planar imaging vs 3D single photon emission CT (SPECT); this can affect the total allowable Y-90 dose delivered and therefore change the effectiveness of the procedure. The case presented demonstrates an 81% decrease in LSF when calculated by SPECT as compared to 2D planar imaging. This case highlights the importance of considering the imaging technique and the potential discrepancies that can arise between planar and SPECT imaging in LSF assessment.
摘要
钇-90（Y-90）放射性栓塞治疗的安全性和有效性部分取决于肺分流分数（LSF）。使用二维平面成像与三维单光子发射计算机断层扫描（SPECT）计算LSF时可能存在显著差异；这会影响所给予的Y-90总允许剂量，从而改变该治疗程序的有效性。所呈现的病例表明，与二维平面成像相比，通过SPECT计算时LSF降低了81%。该病例突出了在LSF评估中考虑成像技术以及平面成像和SPECT成像之间可能出现的差异的重要性。
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