Thachil Jecko, Iba Toshiaki
Juntendo Iji Zasshi. 2023 Dec 20;69(6):463-465. doi: 10.14789/jmj.JMJ23-0038-P. eCollection 2023.
Disseminated intravascular coagulation (DIC) is a common and critical complication in various diseases. There are several diagnostic criteria, such as the International Society on Thrombosis and Haemostasis (ISTH) criteria, the Japanese Society on Thrombosis and Hemostasis (JSTH) criteria, and the Japanese Association for Acute Medicine (JAAM) criteria. Due to the strengths and drawbacks inherent in each diagnostic criterion, it has the potential to cause confusion in clinical settings. It is possible to increase the specificity by making a complex criterion but simple and easy-to-use criteria are demanded in practice. To establish pragmatic criteria using readily available biomarkers, the ISTH focused on DIC arising from sepsis and released sepsis-induced coagulopathy criteria (SIC). A similar approach will aid in constructing a practical diagnostic criterion tailored to each specific background.
弥散性血管内凝血(DIC)是多种疾病中常见且严重的并发症。有多种诊断标准,如国际血栓与止血学会(ISTH)标准、日本血栓与止血学会(JSTH)标准以及日本急性医学协会(JAAM)标准。由于每种诊断标准都有其固有的优缺点,在临床环境中可能会导致混淆。制定复杂的标准有可能提高特异性,但在实际应用中需要简单易用的标准。为了利用易于获得的生物标志物建立实用标准,ISTH关注脓毒症引起的DIC并发布了脓毒症诱导的凝血病标准(SIC)。类似的方法将有助于构建针对每个特定背景的实用诊断标准。