Ehrlich April, Oh Esther S, Ahmed Shaista
Division of Geriatric Medicine and Gerontology, Department of Medicine, The Johns Hopkins University, 5200, Eastern Avenue, Suite , 2200 Baltimore, MD, 21224, USA.
Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University, Baltimore, MD, USA.
Curr Geriatr Rep. 2024 Jun;13(2):52-60. doi: 10.1007/s13670-024-00413-y. Epub 2024 Apr 3.
Emergency departments (EDs) are facing an epidemic of overcrowding and ED boarding, particularly of older adults who often present with, or develop, delirium in the ED. Delirium is associated with increased complications, longer hospital length of stay, mortality, and costs to the healthcare system. However, we only have limited knowledge of how to successfully prevent and treat delirium in the ED in a pragmatic, sustainable, and cost-effective way. We present a narrative review of recent literature of delirium prevention and treatment programs in the ED. We aim to describe the components of successful delirium management strategies to be used by EDs in building delirium management programs.
We reviewed 10 studies (2005-2023) that report delirium interventions in the ED, and describe the different components of these interventions that have been studied. These interventions included: optimizing hemodynamics and oxygenation, treating pain, hydration and nutrition support, avoiding sedative hypnotics, antipsychotics and anticholinergics, promoting sleep, sensory stimulation, limiting the time spent in the ED, educating providers and staff, and developing multidisciplinary delirium protocols integrated into the electronic health record.
Through our narrative review of the recent literature on delirium prevention and treatment programs in the ED, we have identified nine components of successful delirium prevention strategies in the ED. We also discuss three high priority areas for further research including identification of most effective components of delirium prevention strategies, conduct of additional high-quality trials in non-hip.
急诊科正面临过度拥挤和急诊科滞留的问题,尤其是老年患者,他们常在急诊科出现谵妄或在急诊科发生谵妄。谵妄与并发症增加、住院时间延长、死亡率上升以及医疗系统成本增加有关。然而,我们对于如何以实用、可持续且具成本效益的方式在急诊科成功预防和治疗谵妄的了解有限。我们对急诊科谵妄预防和治疗项目的近期文献进行了叙述性综述。我们旨在描述成功的谵妄管理策略的组成部分,供急诊科用于建立谵妄管理项目。
我们回顾了10项(2005 - 2023年)报告急诊科谵妄干预措施的研究,并描述了这些干预措施中已被研究的不同组成部分。这些干预措施包括:优化血流动力学和氧合、治疗疼痛、提供水化和营养支持、避免使用镇静催眠药、抗精神病药和抗胆碱能药物、促进睡眠、进行感觉刺激、限制在急诊科的停留时间、对医护人员进行教育,以及制定纳入电子健康记录的多学科谵妄诊疗方案。
通过对急诊科谵妄预防和治疗项目近期文献的叙述性综述,我们确定了急诊科成功的谵妄预防策略的九个组成部分。我们还讨论了三个需要进一步研究的高度优先领域,包括确定谵妄预防策略中最有效的组成部分、在非髋部进行更多高质量试验。