Crisanti A S, Page K, Saavedra J L, Kincaid T, Caswell C M, Waldorf V A
Department of Psychiatry and Behavioral Sciences, University of New Mexico Health Sciences Center, Albuquerque, NM, United States.
Department of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM, United States.
Front Psychiatry. 2024 May 16;15:1330436. doi: 10.3389/fpsyt.2024.1330436. eCollection 2024.
In 2020, New Mexico had the highest alcohol related death and the 11th highest drug overdose rate in the U.S. Towards the long-term goal of addressing this public health problem, we are implementing and evaluating an multi-level intervention designed to identify adults at risk of substance use disorder (SUD) and encourage linkage to and retention in treatment. The first level includes equipping the ED and medical inpatient units of a safety-net hospital with a method to screen individuals at risk of a SUD. The second level includes Seeking Safety (SS), a trauma-specific treatment for PTSD and SUD; and pharmacotherapy for SUD. Motivational Interviewing (MI) is used throughout both levels. Using the SPIRIT guidelines and checklist, this study protocol describes the multi-level intervention and the methodology we are using to assess feasibility and effectiveness.
We are using a Type 1 hybrid implementation design with a non-randomized approach (ISRCTN registration # ISRCTN33100750). We aim to enroll 110 adults ( ) who screen positive for unhealthy use of alcohol, prescription medications (used nonmedically) and/or illicit drugs. Peer support workers are responsible for screening, using MI to increase engagement in screening and treatment and delivery of SS. Pharmacotherapy is provided by addiction clinical specialists. Treatment is provided post hospital discharge via telehealth to increase access to care. Participants are identified through (1) review of electronic health records for individuals with a chief or secondary complaint or mental health condition relating to alcohol and/or other drug use, (2) referrals from clinical staff and (3) screening in the ED and medical inpatient units. Feasibility is being measured through process data. Effectiveness will be determined by changes in two primary outcomes: (i) PTSD symptom severity; and (ii) substance use.
Our study will expand on research related to the implementation of treatment strategies for patients presenting at EDs and admitted to medical inpatients units wherein there is a significant window of opportunity to link patients with follow-up behavioral and clinical services for alcohol and/or drug misuse. The challenges associated with implementation and strategies that have been helpful to address these challenges will further inform the field.
2020年,新墨西哥州的酒精相关死亡率在美国最高,药物过量使用率排名第11。为实现解决这一公共卫生问题的长期目标,我们正在实施和评估一项多层次干预措施,旨在识别有物质使用障碍(SUD)风险的成年人,并鼓励他们接受治疗并持续接受治疗。第一层次包括为一家安全网医院的急诊科和内科住院部配备一种方法,以筛查有SUD风险的个体。第二层次包括“寻求安全”(SS),这是一种针对创伤后应激障碍(PTSD)和SUD的特定创伤治疗方法;以及针对SUD的药物治疗。在两个层次中都使用动机性访谈(MI)。本研究方案使用SPIRIT指南和清单,描述了多层次干预措施以及我们用于评估可行性和有效性的方法。
我们正在使用一种非随机方法的1型混合实施设计(ISRCTN注册编号:ISRCTN33100750)。我们的目标是招募110名成年人( ),他们在酒精、处方药(非医疗用途)和/或非法药物的不健康使用方面筛查呈阳性。同伴支持工作者负责筛查,使用MI来提高对筛查和治疗的参与度,并提供SS。药物治疗由成瘾临床专家提供。出院后通过远程医疗提供治疗,以增加获得护理的机会。通过以下方式识别参与者:(1)审查电子健康记录,查找有与酒精和/或其他药物使用相关的主要或次要投诉或心理健康状况的个体;(2)临床工作人员的转诊;(3)在急诊科和内科住院部进行筛查。通过过程数据来衡量可行性。有效性将由两个主要结果的变化来确定:(i)PTSD症状严重程度;(ii)物质使用情况。
我们的研究将扩展与急诊科患者和内科住院患者治疗策略实施相关的研究,在这些患者中,有一个将患者与酒精和/或药物滥用的后续行为和临床服务联系起来的重要机会窗口。与实施相关的挑战以及有助于应对这些挑战的策略将进一步为该领域提供信息。