Suppr超能文献

在美国 HEALing(帮助终结阿片类药物滥用长期危害)社区研究中,减少人们对扩大过量用药教育、纳洛酮分发以及阿片类药物使用障碍治疗药物规模的认知障碍。

Reducing perceived barriers to scaling up overdose education and naloxone distribution and medications for opioid use disorder in the United States in the HEALing (Helping End Addiction Long-Term®) communities study.

机构信息

Department of Family and Community Medicine, Ohio State University, Suite 5000, 700 Ackerman Rd, Columbus, OH 43202, USA.

Center for Official Statistics, RTI International, 3040 East Cornwallis Road, PO Box 12194, Research Triangle Park, NC 27709, USA.

出版信息

Prev Med. 2024 Aug;185:108034. doi: 10.1016/j.ypmed.2024.108034. Epub 2024 Jun 8.

Abstract

BACKGROUND

Scaling up overdose education and naloxone distribution (OEND) and medications for opioid use disorder (MOUD) is needed to reduce opioid overdose deaths, but barriers are pervasive. This study examines whether the Communities That HEAL (CTH) intervention reduced perceived barriers to expanding OEND and MOUD in healthcare/behavioral health, criminal-legal, and other/non-traditional venues.

METHODS

The HEALing (Helping End Addiction Long-Term®) Communities Study is a parallel, wait-list, cluster randomized trial testing the CTH intervention in 67 communities in the United States. Surveys administered to coalition members and key stakeholders measured the magnitude of perceived barriers to scaling up OEND and MOUD in November 2019-January 2020, May-June 2021, and May-June 2022. Multilevel linear mixed models compared Wave 1 (intervention) and Wave 2 (wait-list control) respondents. Interactions by rural/urban status and research site were tested.

RESULTS

Wave 1 respondents reported significantly greater reductions in mean scores for three outcomes: perceived barriers to scaling up OEND in Healthcare/Behavioral Health Venues (-0.26, 95% confidence interval, CI: -0.48, -0.05, p = 0.015), OEND in Other/Non-traditional Venues (-0.53, 95% CI: - 0.84, -0.22, p = 0.001) and MOUD in Other/Non-traditional Venues (-0.34, 95% CI: -0.62, -0.05, p = 0.020). There were significant interactions by research site for perceived barriers to scaling up OEND and MOUD in Criminal-Legal Venues. There were no significant interactions by rural/urban status.

DISCUSSION

The CTH Intervention reduced perceived barriers to scaling up OEND and MOUD in certain venues, with no difference in effectiveness between rural and urban communities. More research is needed to understand facilitators and barriers in different venues.

摘要

背景

为了降低阿片类药物过量死亡人数,需要扩大过量用药教育和纳洛酮分发(OEND)以及阿片类药物使用障碍(MOUD)治疗药物的应用范围,但存在着广泛的障碍。本研究旨在探讨 Communities That HEAL(CTH)干预措施是否降低了医疗/行为健康、刑事法律和其他/非传统场所扩大 OEND 和 MOUD 治疗的感知障碍。

方法

HEALing(帮助长期戒毒)社区研究是一项平行、等待名单、集群随机试验,在美国 67 个社区测试 CTH 干预措施。2019 年 11 月至 2020 年 1 月、2021 年 5 月至 6 月和 2022 年 5 月至 6 月期间,向联盟成员和主要利益攸关方发放的调查评估了扩大 OEND 和 MOUD 治疗的感知障碍的程度。多水平线性混合模型比较了第 1 波(干预)和第 2 波(等待名单对照)的受访者。测试了农村/城市状态和研究地点的交互作用。

结果

第 1 波受访者报告的三个结果的平均得分显著降低:医疗/行为健康场所扩大 OEND 的感知障碍(-0.26,95%置信区间,CI:-0.48,-0.05,p=0.015)、其他/非传统场所扩大 OEND 的感知障碍(-0.53,95%CI:-0.84,-0.22,p=0.001)和其他/非传统场所扩大 MOUD 的感知障碍(-0.34,95%CI:-0.62,-0.05,p=0.020)。刑事法律场所扩大 OEND 和 MOUD 的感知障碍存在显著的研究地点交互作用。农村/城市状态无显著交互作用。

讨论

CTH 干预措施降低了某些场所扩大 OEND 和 MOUD 治疗的感知障碍,农村和城市社区的干预效果没有差异。需要进一步研究不同场所的促进因素和障碍。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验