Marley Grace, Shubel Caroline, Thorpe Carolyn T, Annis Izabela E, Delamater Paul, Carpenter Delesha, Ostrach Bayla
Division of Pharmaceutical Outcomes and Policy, University of North Carolina Eshelman School of Pharmacy, Chapel Hill, North Carolina, USA.
South East Area Health Education Center, Wilmington, North Carolina, USA.
J Rural Health. 2025 Jun;41(3):e70069. doi: 10.1111/jrh.70069.
The objective of this study was to comprehensively identify the programs that distribute naloxone at no-cost in North Carolina, identify where and to whom these programs distribute naloxone, and evaluate disparities in reported naloxone distribution by geographic area.
A cross-sectional online survey was delivered to potential no-cost naloxone distributors in NC identified by a community advisory panel. Descriptive statistics and Fisher exact tests were utilized to identify disparities in naloxone access by population served (people who use drugs, people who inject drugs) and location of naloxone distribution (rural; urban/suburban).
Approximately 76.5% (241/315) of respondents representing 341 different programs reported that their program(s) distributed no-cost naloxone to community members. Programs represented included health departments (n = 81), treatment programs/centers (n = 59), and syringe service programs(SSPs) (n = 41), among others. Programs reported distributing naloxone most frequently to people who use drugs (94.2%) and people with a substance use disorder history (94.3%). No-cost naloxone distribution was reported less frequently to all patient populations in rural ZIP codes when compared to urban ZIP codes, including justice-involved populations (86.4% vs. 98.3%) and individuals leaving treatment or detox (87.9% vs. 98.6%).
This study indicates that although most areas in NC were served by at least one no-cost naloxone program, distribution to rural populations may be limited, indicating a need for increased public investment in no-cost naloxone distribution to populations at greatest risk of overdose.
本研究的目的是全面识别北卡罗来纳州免费分发纳洛酮的项目,确定这些项目在何处以及向谁分发纳洛酮,并评估按地理区域报告的纳洛酮分发差异。
向社区咨询小组确定的北卡罗来纳州潜在免费纳洛酮分发商进行了一项横断面在线调查。使用描述性统计和费舍尔精确检验来确定按服务人群(吸毒者、注射吸毒者)和纳洛酮分发地点(农村;城市/郊区)的纳洛酮获取差异。
代表341个不同项目的约76.5%(241/315)的受访者报告称,他们的项目向社区成员免费分发纳洛酮。所代表的项目包括卫生部门(n = 81)、治疗项目/中心(n = 59)和注射器服务项目(SSP)(n = 41)等。项目报告称,最常向吸毒者(94.2%)和有物质使用障碍病史的人(94.3%)分发纳洛酮。与城市邮政编码地区相比,农村邮政编码地区向所有患者群体免费分发纳洛酮的频率较低,包括涉及司法的人群(86.4%对98.3%)和离开治疗或戒毒机构的个人(87.9%对98.6%)。
本研究表明,尽管北卡罗来纳州的大多数地区至少有一个免费纳洛酮项目提供服务,但向农村人口的分发可能有限,这表明需要增加对免费纳洛酮分发的公共投资,以惠及过量用药风险最高的人群。