Centre for Academic Mental Health, University of Bristol, Bristol Medical School, Bristol.
School of Medicine, Keele University, Keele.
Br J Gen Pract. 2024 Oct 31;74(748):e735-e741. doi: 10.3399/BJGP.2024.0091. Print 2024 Nov.
Between 2003 and 2018, incident prescriptions of beta-blockers for anxiety increased substantially, particularly for young adults. National Institute for Health and Care Excellence guidance for anxiety does not recommend beta-blockers, probably due to a lack of evidence to support such use. Recent reports have highlighted the potential risks of beta-blockers.
To understand when and why GPs prescribe beta-blockers for people with anxiety.
In-depth interviews with 17 GPs in Bristol and the surrounding areas.
Interviews were held by telephone or video call. A topic guide was used to ensure consistency across interviews. Interviews were audio-recorded, transcribed verbatim, and analysed thematically.
Many GPs viewed beta-blockers as 'low risk', particularly for young adults. Some GPs viewed beta-blockers as an alternative to benzodiazepines, acting quickly and not leading to dependence. GPs reflected that some patients appeared to want an 'immediate fix' to their symptoms, which GPs thought beta-blockers could potentially offer. This is salient in light of substantial waiting lists for talking therapies and delays in antidepressants taking effect. GPs described how some patients seemed more willing to try beta-blockers than antidepressants, as patients did not perceive them as 'mental health drugs' and therefore viewed them as potentially more acceptable and less stigmatising. Further, GPs viewed beta-blockers as 'patient-led', with patients managing their own dose and frequency, without GP input.
Many GPs believe that beta-blockers have a role to play in the management of anxiety. Given recent increases in the prescribing of these drugs in primary care, there is a need to assess their safety and effectiveness as a treatment for people with anxiety disorders.
2003 年至 2018 年间,用于焦虑症的β受体阻滞剂的偶发性处方大量增加,尤其是在年轻人中。英国国家卫生与保健优化研究所(National Institute for Health and Care Excellence)针对焦虑症的指导意见不推荐使用β受体阻滞剂,这可能是由于缺乏支持此类用途的证据。最近的报告强调了β受体阻滞剂的潜在风险。
了解全科医生为何以及何时为焦虑症患者开β受体阻滞剂。
在布里斯托尔及其周边地区对 17 名全科医生进行深入访谈。
通过电话或视频通话进行访谈。使用主题指南确保访谈具有一致性。访谈内容进行了录音、逐字转录,并进行了主题分析。
许多全科医生认为β受体阻滞剂“风险低”,尤其是对年轻人而言。一些全科医生认为β受体阻滞剂可替代苯二氮䓬类药物,起效快且不会导致依赖性。全科医生认为,一些患者似乎希望他们的症状得到“立即缓解”,他们认为β受体阻滞剂可能提供这种效果。鉴于心理咨询的等候名单很长,以及抗抑郁药起效延迟,这一点尤为重要。全科医生描述了一些患者似乎更愿意尝试β受体阻滞剂而非抗抑郁药,因为患者不认为它们是“精神健康药物”,因此认为它们可能更易接受,且耻辱感较低。此外,全科医生认为β受体阻滞剂是“患者主导”的,患者自行管理剂量和频率,而无需全科医生的指导。
许多全科医生认为β受体阻滞剂在焦虑症的治疗中具有一定作用。鉴于这些药物在初级保健中开具的处方最近有所增加,因此有必要评估它们作为焦虑症治疗药物的安全性和有效性。