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促进行为改变的母婴健康干预:洪都拉斯的一项人群水平整群随机对照试验。

Maternal and child health intervention to promote behaviour change: a population-level cluster-randomised controlled trial in Honduras.

机构信息

Yale Institute for Network Science, Yale University, New Haven, Connecticut, USA.

Institute for Health Equity Research, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

出版信息

BMJ Open. 2024 Jun 10;14(6):e060784. doi: 10.1136/bmjopen-2022-060784.

Abstract

OBJECTIVES

To assess the efficacy of a sustained educational intervention to affect diverse outcomes across the pregnancy and infancy timeline.

SETTING

A multi-arm cluster-randomised controlled trial in 99 villages in Honduras' Copán region, involving 16 301 people in 5633 households from October 2015 to December 2019.

PARTICIPANTS

Residents aged 12 and older were eligible. A photographic census involved 93% of the population, with 13 881 and 10 263 individuals completing baseline and endline surveys, respectively.

INTERVENTION

22-month household-based counselling intervention aiming to improve practices, knowledge and attitudes related to maternal, neonatal and child health.

PRIMARY AND SECONDARY OUTCOME MEASURES

Primary outcomes were prenatal/postnatal care behaviours, facility births, exclusive breast feeding, parental involvement, treatment of diarrhoea and respiratory illness, reproductive health, and gender/reproductive norms. Secondary outcomes were knowledge and attitudes related to the primary outcomes.

RESULTS

Parents targeted for the intervention were 16.4% (95% CI 3.1%-29.8%, p=0.016) more likely to have their newborn's health checked in a health facility within 3 days of birth; 19.6% (95% CI 4.2%-35.1%, p=0.013) more likely to not wrap a fajero around the umbilical cord in the first week after birth; and 8.9% (95% CI 0.3%-17.5%, p=0.043) more likely to report that the mother breast fed immediately after birth. Changes in knowledge and attitudes related to these primary outcomes were also observed. We found no significant effect on various other practices.

CONCLUSION

A sustained counselling intervention delivered in the home setting by community health workers can meaningfully change practices, knowledge and attitudes related to proper newborn care following birth, including professional care-seeking, umbilical cord care and breast feeding.

TRIAL REGISTRATION NUMBER

NCT02694679.

摘要

目的

评估持续教育干预对妊娠和婴儿期时间线上多种结果的影响。

背景

这是一项在洪都拉斯科潘地区 99 个村庄进行的多臂群组随机对照试验,涉及 2015 年 10 月至 2019 年 12 月期间 5633 户家庭中的 16301 人。

参与者

年龄在 12 岁及以上的居民有资格参加。摄影人口普查涉及 93%的人口,分别有 13881 人和 10263 人完成了基线和期末调查。

干预措施

为期 22 个月的基于家庭的咨询干预措施,旨在改善与母婴、新生儿和儿童健康相关的实践、知识和态度。

主要和次要结果测量

主要结果是产前/产后护理行为、医疗机构分娩、纯母乳喂养、父母参与、腹泻和呼吸道疾病治疗、生殖健康以及性别/生殖规范。次要结果是与主要结果相关的知识和态度。

结果

接受干预的父母让新生儿在出生后 3 天内到医疗机构进行健康检查的可能性高 16.4%(95%置信区间为 3.1%-29.8%,p=0.016);不将 fajero 包裹在脐带周围的可能性高 19.6%(95%置信区间为 4.2%-35.1%,p=0.013);以及报告母亲在出生后立即进行母乳喂养的可能性高 8.9%(95%置信区间为 0.3%-17.5%,p=0.043)。还观察到与这些主要结果相关的知识和态度的变化。我们没有发现对各种其他做法的显著影响。

结论

由社区卫生工作者在家中提供的持续咨询干预措施,可以显著改变与新生儿出生后适当护理相关的做法、知识和态度,包括寻求专业护理、脐带护理和母乳喂养。

试验注册

NCT02694679。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5096/11168147/a659eef691f8/bmjopen-2022-060784f01.jpg

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