Department of Neonatology, KIMS Health, Trivandrum, Kerala, India.
Department of Neonatology, KIMS Health, Trivandrum, Kerala, India. Correspondence to: Dr Femitha Pournami, Senior consultant and Academic Coordinator, Department of Neonatology, KIMS Health, Trivandrum Kerala, India.
Indian Pediatr. 2024 Jul 15;61(7):668-670. Epub 2024 Jun 7.
Very preterm infants often need red blood cell transfusions (RBCT) during intensive care and are at risk of iron overload. This study reviewed the records of 65 very preterm neonates who required at least one RBCT to ascertain the iron status using serum ferritin levels at 4-6 weeks age before oral iron was commenced. High serum ferritin level was found in 52.3% (n = 34) neonates. Need for > 1RBCT was significantly and independently associated with iron excess (P < 0.001). Increased ferritin noted following transfusions in neonatal period can have implications for determining the appropriate time for starting iron supplementation in this subgroup of neonates.
早产儿在重症监护期间通常需要输血（RBCT），并且有铁过载的风险。本研究回顾了 65 名需要至少进行一次 RBCT 的极低出生体重儿的记录，以确定在开始口服铁剂之前，4-6 周龄时血清铁蛋白水平的铁状态。结果发现，52.3%（n=34）的新生儿血清铁蛋白水平较高。需要输注>1 次 RBCT 与铁过量显著相关（P<0.001）。新生儿期输血后出现的铁蛋白升高可能会影响确定该亚组新生儿开始补铁的适当时间。
