Universidad Peruana de Ciencias Aplicadas, Lima, Peru.
Department of Internal Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa.
Am J Trop Med Hyg. 2024 Jun 11;111(2):312-316. doi: 10.4269/ajtmh.23-0684. Print 2024 Aug 7.
Neurobrucellosis, caused by Brucella species, is a zoonotic infection that may involve the central nervous system. Although uncommon, it can manifest as a solitary intracranial mass. We report a case of neurobrucellosis in a 25-year-old woman from Peru who presented with headache, weight loss, and right-side hemiparesis and paresthesia. A contrast-enhanced magnetic resonance imaging scan revealed an intracerebral mass in the left temporal lobe. Serum testing subsequently were positive. Brain biopsy demonstrated non-necrotizing granulomas without malignant cells. Neurobrucellosis should be considered in the differential diagnosis of brain space occupying lesions in endemic countries.
神经布鲁菌病是由布鲁氏菌引起的一种人畜共患感染，可能累及中枢神经系统。虽然不常见，但它可表现为单一颅内肿块。我们报告一例来自秘鲁的 25 岁女性神经布鲁菌病，表现为头痛、体重减轻和右侧偏瘫及感觉异常。增强磁共振成像扫描显示左颞叶脑内肿块。随后血清检测呈阳性。脑活检显示无坏死性肉芽肿，无恶性细胞。在流行地区，对于脑占位病变的鉴别诊断应考虑神经布鲁菌病。
