Marcandella Elena Sofia, Boscarelli Alessandro, Murru Flora-Maria, Abbracciavento Giuseppe, Spazzapan Peter, Schleef Jurgen
Pediatric Surgery Division, Women's and Children's Health Department, University of Padua, Padua, Italy.
Department of Pediatric Surgery and Urology, Institute of Maternal and Child Health - Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) "Burlo Garofolo", Trieste, Italy.
Front Oncol. 2024 May 28;14:1400335. doi: 10.3389/fonc.2024.1400335. eCollection 2024.
Schwannomas are benign, slow-growing tumors originating from the Schwann cells of nerve sheaths. Extracranial schwannomas are rare, particularly in pediatric populations. Here, we report the case of a hypoglossal schwannoma in a 15-year-old male who experienced tongue paresthesia and fasciculations and difficulty swallowing two years before hospital admission. Magnetic resonance imaging showed an oval mass with sharp and regular limits of approximately 45 × 29 × 25 mm in the cranial portion of the right carotid adipose space, caudal to the right carotid and lateral foramen. The patient underwent surgery, and a histological examination confirmed a schwannoma of the hypoglossal nerve. Six months after surgery, the patient was symptom-free. The literature on schwannomas of the hypoglossal nerve is scarce, with only a few previously reported cases in the adult population. Despite their rarity, schwannomas should be considered in the differential diagnosis of masses located in the neck that present with lingual and occasionally auditory symptoms, even in pediatric patients. Surgical resection is recommended and has a low risk of long-term recurrence.
神经鞘瘤是起源于神经鞘雪旺细胞的良性、生长缓慢的肿瘤。颅外神经鞘瘤罕见,尤其在儿科人群中。在此,我们报告一例15岁男性舌下神经鞘瘤病例,该患者在入院前两年出现舌感觉异常、肌束震颤和吞咽困难。磁共振成像显示在右颈动脉脂肪间隙的颅部、右颈动脉尾侧和外侧孔处有一个椭圆形肿块,边界清晰规则,大小约为45×29×25毫米。患者接受了手术,组织学检查证实为舌下神经鞘瘤。术后六个月,患者无症状。关于舌下神经鞘瘤的文献稀少,此前仅在成人人群中有少数病例报道。尽管神经鞘瘤罕见,但对于出现舌部症状且偶尔有听觉症状的颈部肿块,即使是儿科患者,在鉴别诊断时也应考虑到神经鞘瘤。建议手术切除,长期复发风险较低。