Pommert Nina Sophie, Puehler Thomas, Voges Inga, Sellers Stephanie, Lutter Georg
Department of Cardiac Surgery, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany.
DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg/Kiel/Luebeck, Kiel, Germany.
Front Cardiovasc Med. 2024 May 20;11:1373840. doi: 10.3389/fcvm.2024.1373840. eCollection 2024.
Transcatheter mitral valve replacement (TMVR) is a valuable treatment option in patients with severe mitral regurgitation. Prior transapical transcatheter aortic valve replacement (TA-TAVR) may complicate the procedure and is therefore considered a relative contraindication. In this case report, the authors describe the successful TMVR as a tertiary cardiac surgery and transapical redo procedure.
An 83-year-old male patient, suffering from dyspnoea and angina, was diagnosed with severe mitral valve regurgitation (MR). He had already undergone cardiac surgery in the form of coronary artery bypass grafting at the age of 64 and TA-TAVR at 79 years. After a failed attempt at mitral valve transcatheter edge-to-edge repair, he opted for TMVR. Pre-TMVR computed tomography simulation was used to analyse possible interactions between the prostheses and to predict the neo-left ventricular outflow tract (neo-LVOT). The operation was carried out without complications. There was no bleeding and the LV function remained unchanged. On MRI, the valves were perfectly aligned without any signs of paravalvular leakage or LVOT obstruction. The patient was discharged seven days postoperatively. At the one-year follow up, there was no need for rehospitalisation and the patient had clinically improved (from NYHA IV to II). Echocardiography demonstrated a mean transvalvular gradient of under 5 mmHg and no residual MR.
A redo transapical access for TMVR as a tertiary cardiac operation can be easily performed. Pre-operative CT suggested good alignment of the aortic and mitral valved stent which was confirmed postoperatively.
经导管二尖瓣置换术(TMVR)是重度二尖瓣反流患者的一种重要治疗选择。既往经心尖经导管主动脉瓣置换术(TA-TAVR)可能使该手术复杂化,因此被视为相对禁忌证。在本病例报告中,作者描述了作为三级心脏手术和经心尖再次手术成功实施TMVR的情况。
一名83岁男性患者,因呼吸困难和心绞痛被诊断为重度二尖瓣反流(MR)。他64岁时已接受冠状动脉旁路移植术形式的心脏手术,79岁时接受TA-TAVR。在二尖瓣经导管缘对缘修复尝试失败后,他选择了TMVR。术前TMVR计算机断层扫描模拟用于分析假体之间可能的相互作用,并预测新的左心室流出道(neo-LVOT)。手术顺利进行,无并发症。无出血,左心室功能保持不变。MRI显示瓣膜完美对齐,无瓣周漏或LVOT梗阻迹象。患者术后7天出院。在1年随访时,无需再次住院,患者临床症状改善(从纽约心脏病协会IV级改善至II级)。超声心动图显示平均跨瓣压差低于5 mmHg,无残余MR。
作为三级心脏手术的TMVR经心尖再次入路可以轻松实施。术前CT提示主动脉和二尖瓣带瓣支架对齐良好,术后得到证实。