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基于互联网的失眠干预对处于高自杀风险的退伍军人自杀意念及相关因素的影响。

Impact of an internet-based insomnia intervention on suicidal ideation and associated correlates in veterans at elevated suicide risk.

机构信息

Dissemination and Training Division, National Center for PTSD, Palo Alto, CA, USA.

Department of Neuroscience, Icahn School of Medicine, New York, NY, USA.

出版信息

Transl Behav Med. 2024 Nov 16;14(11):673-683. doi: 10.1093/tbm/ibae032.

Abstract

Improving public health approaches to suicide prevention requires scalable evidence-based interventions that can be easily disseminated. Given empirical data supporting the association between insomnia and suicide risk, internet-delivered insomnia interventions are promising candidates to meet this need. The purpose of this study was to examine whether an unguided internet-delivered cognitive-behavioral therapy for insomnia (iCBT-I) improved insomnia severity, suicidal ideation (SI), and suicide risk correlates (depression, post-traumatic stress disorder, anxiety, hostility, belongingness, hopelessness, agitation, irritability, concentration) in a sample of veterans. Secondary data analysis of Operation Enduring Freedom, Operation Iraqi Freedom, and Operation New Dawn veterans (n = 50) with clinically significant insomnia and elevated SI drawn from a larger randomized controlled trial (RCT) of an iCBT-I, Sleep Healthy Using the Internet (SHUTi). Two-sample t-tests or Wilcoxon rank sum tests were used to evaluate between-group differences (SHUTi vs. Insomnia Education Website control) in symptom improvement from baseline to post-intervention. SHUTi participants experienced a significant improvement in insomnia severity (P < .001; d = -1.08) and a non-significant with small (subthreshold medium) effect size reduction of SI (P = .17, d = 0.40), compared to control participants. Significant improvement in hopelessness was observed (medium effect size), with non-significant small to medium effect size reductions in most remaining suicide risk correlates. Self-administered iCBT-I was associated with improvements in insomnia severity in veterans at elevated risk for suicide. These preliminary findings suggest that SI and suicide risk correlates may improve following an iCBT-I intervention, demonstrating the need for future well-powered iCBT-I RCTs targeted for populations at elevated suicide risk.

摘要

改善预防自杀的公共卫生方法需要可扩展的基于证据的干预措施,这些措施易于传播。鉴于支持失眠与自杀风险之间关联的经验数据,基于互联网的失眠干预措施是满足这一需求的有希望的候选者。本研究的目的是检验在一个退伍军人样本中,一种未经指导的基于互联网的认知行为疗法治疗失眠症(iCBT-I)是否能改善失眠严重程度、自杀意念(SI)和自杀风险相关因素(抑郁、创伤后应激障碍、焦虑、敌意、归属感、绝望、激动、易怒、注意力集中)。这是对来自较大规模随机对照试验(RCT)的具有临床意义的失眠和升高的 SI 的作战持久自由行动、伊拉克自由行动和新黎明行动的退伍军人(n = 50)的二次数据分析,这些退伍军人接受了 iCBT-I,即使用互联网保持睡眠健康(SHUTi)的治疗。采用两样本 t 检验或 Wilcoxon 秩和检验评估从基线到干预后症状改善的组间差异(SHUTi 与失眠教育网站对照)。与对照组相比,SHUTi 参与者的失眠严重程度显著改善(P <.001;d = -1.08),SI 略有改善(P =.17,d = 0.40),但效果大小不显著。观察到绝望感显著改善(中等效果大小),大多数剩余的自杀风险相关因素的效果大小从较小到中等有所降低。自我管理的 iCBT-I 与处于自杀风险升高的退伍军人的失眠严重程度改善有关。这些初步发现表明,在接受 iCBT-I 干预后,SI 和自杀风险相关因素可能会改善,这表明需要针对自杀风险升高的人群进行未来具有更大效力的 iCBT-I RCT。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2b3/11568844/f4d4f205c9b5/ibae032_fig1.jpg

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