Dissemination and Training Division, National Center for PTSD, Palo Alto, CA, USA.
Department of Neuroscience, Icahn School of Medicine, New York, NY, USA.
Transl Behav Med. 2024 Nov 16;14(11):673-683. doi: 10.1093/tbm/ibae032.
Improving public health approaches to suicide prevention requires scalable evidence-based interventions that can be easily disseminated. Given empirical data supporting the association between insomnia and suicide risk, internet-delivered insomnia interventions are promising candidates to meet this need. The purpose of this study was to examine whether an unguided internet-delivered cognitive-behavioral therapy for insomnia (iCBT-I) improved insomnia severity, suicidal ideation (SI), and suicide risk correlates (depression, post-traumatic stress disorder, anxiety, hostility, belongingness, hopelessness, agitation, irritability, concentration) in a sample of veterans. Secondary data analysis of Operation Enduring Freedom, Operation Iraqi Freedom, and Operation New Dawn veterans (n = 50) with clinically significant insomnia and elevated SI drawn from a larger randomized controlled trial (RCT) of an iCBT-I, Sleep Healthy Using the Internet (SHUTi). Two-sample t-tests or Wilcoxon rank sum tests were used to evaluate between-group differences (SHUTi vs. Insomnia Education Website control) in symptom improvement from baseline to post-intervention. SHUTi participants experienced a significant improvement in insomnia severity (P < .001; d = -1.08) and a non-significant with small (subthreshold medium) effect size reduction of SI (P = .17, d = 0.40), compared to control participants. Significant improvement in hopelessness was observed (medium effect size), with non-significant small to medium effect size reductions in most remaining suicide risk correlates. Self-administered iCBT-I was associated with improvements in insomnia severity in veterans at elevated risk for suicide. These preliminary findings suggest that SI and suicide risk correlates may improve following an iCBT-I intervention, demonstrating the need for future well-powered iCBT-I RCTs targeted for populations at elevated suicide risk.
改善预防自杀的公共卫生方法需要可扩展的基于证据的干预措施,这些措施易于传播。鉴于支持失眠与自杀风险之间关联的经验数据,基于互联网的失眠干预措施是满足这一需求的有希望的候选者。本研究的目的是检验在一个退伍军人样本中,一种未经指导的基于互联网的认知行为疗法治疗失眠症(iCBT-I)是否能改善失眠严重程度、自杀意念(SI)和自杀风险相关因素(抑郁、创伤后应激障碍、焦虑、敌意、归属感、绝望、激动、易怒、注意力集中)。这是对来自较大规模随机对照试验(RCT)的具有临床意义的失眠和升高的 SI 的作战持久自由行动、伊拉克自由行动和新黎明行动的退伍军人(n = 50)的二次数据分析,这些退伍军人接受了 iCBT-I,即使用互联网保持睡眠健康(SHUTi)的治疗。采用两样本 t 检验或 Wilcoxon 秩和检验评估从基线到干预后症状改善的组间差异(SHUTi 与失眠教育网站对照)。与对照组相比,SHUTi 参与者的失眠严重程度显著改善(P <.001;d = -1.08),SI 略有改善(P =.17,d = 0.40),但效果大小不显著。观察到绝望感显著改善(中等效果大小),大多数剩余的自杀风险相关因素的效果大小从较小到中等有所降低。自我管理的 iCBT-I 与处于自杀风险升高的退伍军人的失眠严重程度改善有关。这些初步发现表明,在接受 iCBT-I 干预后,SI 和自杀风险相关因素可能会改善,这表明需要针对自杀风险升高的人群进行未来具有更大效力的 iCBT-I RCT。