Paving the ROCKy Path to Novel Antifibrotics.
作者信息
Knipe Rachel S, Gosens Reinoud
机构信息
Division of Pulmonary and Critical Care Medicine Massachusetts General Hospital Boston, Massachusetts.
Department of Molecular Pharmacology University of Groningen Groningen, the Netherlands.
出版信息
Am J Respir Cell Mol Biol. 2024 Oct;71(4):381-382. doi: 10.1165/rcmb.2024-0224ED.
Abstract
摘要
相似文献
1
Paving the ROCKy Path to Novel Antifibrotics.
Am J Respir Cell Mol Biol. 2024 Oct;71(4):381-382. doi: 10.1165/rcmb.2024-0224ED.
2
Real-world impact of antifibrotics on prognosis in patients with progressive fibrosing interstitial lung disease.
RMD Open. 2023 Jan;9(1). doi: 10.1136/rmdopen-2022-002667.
3
Antifibrotics and mortality in idiopathic pulmonary fibrosis: external validity and avoidance of immortal time bias.
Respir Res. 2024 Jul 31;25(1):293. doi: 10.1186/s12931-024-02922-y.
4
Switching antifibrotics in patients with idiopathic pulmonary fibrosis: a multi-center retrospective cohort study.
BMC Pulm Med. 2021 Jul 12;21(1):221. doi: 10.1186/s12890-021-01587-3.
5
Tolerability and efficacy of second-line antifibrotics in patients with idiopathic pulmonary fibrosis.
Pulm Pharmacol Ther. 2021 Dec;71:102099. doi: 10.1016/j.pupt.2021.102099. Epub 2021 Nov 15.
6
Antifibrotics for COVID-19 related lung fibrosis: Agents with benefits?
Adv Respir Med. 2021;89(2):231-233. doi: 10.5603/ARM.a2021.0023.
7
Paving the rocky road to managerial success.
Superv Manage. 1979 Mar;24(3):9-13.
8
Assessment and Feedback Control of Paving Quality of Earth-Rock Dam Based on OODA Loop.
Sensors (Basel). 2021 Nov 22;21(22):7756. doi: 10.3390/s21227756.
9
Antifibrotics in the Management of Rheumatoid Arthritis-Associated Interstitial Lung Disease: Prospective Real-World Experience From an Interstitial Lung Disease Clinic in India.
Cureus. 2024 Jun 30;16(6):e63518. doi: 10.7759/cureus.63518. eCollection 2024 Jun.
10
Does continuation of antifibrotics before lung transplantation influence post-transplant outcomes in patients with idiopathic pulmonary fibrosis?
Interact Cardiovasc Thorac Surg. 2022 Jan 18;34(2):250-254. doi: 10.1093/icvts/ivab237.
本文引用的文献
1
Novel Small-Molecule ROCK2 Inhibitor GNS-3595 Attenuates Pulmonary Fibrosis in Preclinical Studies.
Am J Respir Cell Mol Biol. 2024 Oct;71(4):430-441. doi: 10.1165/rcmb.2023-0401OC.
2
ROCK2 Inhibition With Belumosudil (KD025) for the Treatment of Chronic Graft-Versus-Host Disease.
J Clin Oncol. 2021 Jun 10;39(17):1888-1898. doi: 10.1200/JCO.20.02754. Epub 2021 Apr 20.
3
Rho-Kinase 1/2 Inhibition Prevents Transforming Growth Factor-β-Induced Effects on Pulmonary Remodeling and Repair.
Front Pharmacol. 2021 Jan 20;11:609509. doi: 10.3389/fphar.2020.609509. eCollection 2020.
4
Collagen-producing lung cell atlas identifies multiple subsets with distinct localization and relevance to fibrosis.
Nat Commun. 2020 Apr 21;11(1):1920. doi: 10.1038/s41467-020-15647-5.
5
The Rho Kinase Isoforms ROCK1 and ROCK2 Each Contribute to the Development of Experimental Pulmonary Fibrosis.
Am J Respir Cell Mol Biol. 2018 Apr;58(4):471-481. doi: 10.1165/rcmb.2017-0075OC.
6
The Function of Rho-Associated Kinases ROCK1 and ROCK2 in the Pathogenesis of Cardiovascular Disease.
Front Pharmacol. 2015 Nov 20;6:276. doi: 10.3389/fphar.2015.00276. eCollection 2015.
7
The Rho kinases: critical mediators of multiple profibrotic processes and rational targets for new therapies for pulmonary fibrosis.
Pharmacol Rev. 2015;67(1):103-17. doi: 10.1124/pr.114.009381.
8
Crucial role of ROCK2 in vascular smooth muscle cells for hypoxia-induced pulmonary hypertension in mice.
Arterioscler Thromb Vasc Biol. 2013 Dec;33(12):2780-91. doi: 10.1161/ATVBAHA.113.301357. Epub 2013 Oct 17.
9
ROCK1 mediates leukocyte recruitment and neointima formation following vascular injury.
J Clin Invest. 2008 May;118(5):1632-44. doi: 10.1172/JCI29226.
Zotero 插件