Department of Surgery and Transplantation, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
CAMES, University of Copenhagen, Copenhagen, Denmark.
J Hepatobiliary Pancreat Sci. 2024 Sep;31(9):625-636. doi: 10.1002/jhbp.12015. Epub 2024 Jun 12.
The incidence of liver tumors requiring surgical treatment continues to increase in elderly patients. This study compared the short-term results of robotic liver surgery (RLS) versus open liver surgery (OLS) for liver tumors in elderly patients.
A prospective database including all patients undergoing liver surgery at Copenhagen University Hospital between July 2019 and July 2022 was managed retrospectively. Short-term surgical outcomes of the two main cohorts (OLS and RLS) and subgroups were compared using propensity score matching (PSM) in elderly patients (age ≥ 70 years) with liver tumors.
A total of 42 matched patients from each group were investigated: the RLS group had significantly larger tumor diameters, less blood loss (821.2 vs. 155.2 mL, p < .001), and shorter hospital stays (6.6 vs. 3.4 days, p < .001). Overall morbidity was comparable, while operative times were longer in the RLS group. The advantages observed with the robotic approach were replicated in the subgroup of minor liver resections.
In patients ≥70 years, RLS for liver tumors results in significantly less blood loss and shorter hospital stays than OLS. RLS, especially minor liver resection, is safe and feasible in elderly patients with liver tumors.
需要手术治疗的肝肿瘤在老年患者中的发病率持续上升。本研究比较了机器人肝手术(RLS)与开腹肝手术(OLS)治疗老年肝肿瘤的短期疗效。
回顾性分析了 2019 年 7 月至 2022 年 7 月哥本哈根大学医院所有接受肝手术的患者的前瞻性数据库。采用倾向评分匹配(PSM)对老年(≥70 岁)肝肿瘤患者的两个主要队列(OLS 和 RLS)和亚组的短期手术结果进行比较。
每组各有 42 例匹配患者被纳入研究:RLS 组的肿瘤直径明显更大,出血量更少(821.2 比 155.2ml,p<.001),住院时间更短(6.6 比 3.4 天,p<.001)。总体发病率相当,而 RLS 组的手术时间更长。机器人手术的优势在较小的肝切除亚组中得到了复制。
在≥70 岁的患者中,RLS 治疗肝肿瘤的出血量明显少于 OLS,住院时间更短。RLS 尤其在对肝肿瘤的老年患者进行小范围肝切除时,是安全可行的。