Inserm, UMR 1229, RMeS, Regenerative Medicine and Skeleton, University of Nantes, ONIRIS, Nantes, France.
Department of Periodontology, Faculty of Dental Surgery, University of Nantes, Nantes, France.
J Oral Implantol. 2024 Oct 1;50(5):552-560. doi: 10.1563/aaid-joi-D-23-00028.
Peri-implantitis is an infectious disease that causes inflammation of the tissue surrounding an implant. The aim of this systematic review of the literature is to assess the effect of the use of lasers in the nonsurgical treatment of peri-implantitis in order to estimate its benefits compared with conventional therapies. The review's protocol has been registered on PROSPERO international prospective register. The research strategy was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The inclusion criteria were as follows: in vivo studies, written in English, measurements of clinical parameters, minimum follow-up at 6 months and with nonsurgical control group, studies about photodynamic therapy, randomized clinical trial, and clinical trial. Electronic (on PubMed, Cochrane, Latin American and Caribbean Health Sciences Literature, and Report Evidence-based Practice Centers databases) and manual searches (in articles' references) were conducted until July 2021. Risk of bias was assessed for each reference thanks to the Cochrane Collaboration's tool. A total of 12 randomized clinical trials, with a high level of evidence, were selected and investigated in this systematic review. A table summarizes data extracted from these articles. It appears that the parameters improve favorably by using lasers, but without any significant difference. In accordance with the analysis of studies, our results show that laser therapy with specific characteristics allows to obtain beneficial therapeutic effects on wound healing in the short and the medium-term concerning the clinical parameters in the nonsurgical treatment of peri-implantitis. Concerning its long-term usefulness, it has yet to be confirmed. However, its benefits remains limited since the results agree that the effects of the laser are similar to those obtained by using conventional therapy.
种植体周围炎是一种感染性疾病，会导致种植体周围组织发炎。本系统评价文献的目的是评估激光在种植体周围炎非手术治疗中的应用效果，以估计其与传统治疗相比的益处。本综述的方案已在 PROSPERO 国际前瞻性注册库中注册。研究策略是根据系统评价和荟萃分析的首选报告项目指南进行的。纳入标准如下：体内研究，用英语书写，测量临床参数，至少随访 6 个月，有非手术对照组，关于光动力疗法的研究，随机临床试验，临床试验。电子搜索（在 PubMed、Cochrane、拉丁美洲和加勒比健康科学文献以及报告循证实践中心数据库）和手动搜索（在文章参考文献中）进行到 2021 年 7 月。通过 Cochrane 协作工具评估了每个参考文献的偏倚风险。在本系统评价中，共选择并研究了 12 项具有高证据水平的随机临床试验。一个表格总结了从这些文章中提取的数据。结果表明，使用激光可以有利地改善参数，但没有显著差异。根据研究分析，我们的结果表明，激光疗法具有特定的特性，在种植体周围炎非手术治疗的短期和中期内，在临床参数方面可以获得有益的治疗效果。关于其长期有效性，仍有待证实。然而，其益处仍然有限，因为结果表明激光的效果与传统治疗方法获得的效果相似。
