The effectiveness, in vitro, of miconazole and ketoconazole combined with tissue conditioners in inhibiting the growth of Candida albicans.

Two recent antifungal agents, miconazole and ketoconazole, were combined with three tissue conditioners and tested in vitro for their effects on the growth of Candida albicans. Studies for comparison were carried out using the earlier antifungal agents, amphotericin B and nystatin. Miconazole and ketoconazole were as effective as nystatin in completely inhibiting the growth of Candida albicans. The ineffectiveness of amphotericin B when combined with tissue conditioners as an antifungal agent was confirmed. (See Addendum p.181.).