Division of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Zhongshan Road 321, Nanjing, 210008, China.
Eur Spine J. 2024 Aug;33(8):2935-2951. doi: 10.1007/s00586-024-08357-9. Epub 2024 Jun 13.
To evaluate different patterns of coronal deformity secondary to ankylosing spondylitis (AS), to propose relevant treatment strategies, and to assess efficacy of asymmetrical pedicle subtraction osteotomy (APSO).
Coronal deformity was defined as coronal Cobb angle over 20º or coronal balance distance (CBD) more than 3 cm. 65 consecutive AS patients with concomitant coronal and sagittal deformity who underwent PSO were included. The average follow-up time was 40.4 months. Radiographic evaluation included coronal Cobb angle and CBD. Furthermore, sagittal parameters were used to assess magnitude and maintenance of kyphosis correction.
Based on curve characteristics, coronal deformity caused by AS included four different radiologic patterns: Pattern I: lumbar scoliosis; Pattern II: C-shaped thoracolumbar curve; Pattern III: trunk shift without major curve; Pattern IV: proximal thoracic scoliosis. APSO was performed for patients in Pattern I to III while conventional PSO was applied for patients in Pattern IV. Significant improvement in all the sagittal parameters were noted in 65 patients without obvious correction loss at the last follow-up. Besides, significant and sustained correction of coronal mal-alignment was identified in 59 APSO-treated patients. Rod fracture occurred in four cases and revision surgery was performed for one case.
According to radiologic manifestations, coronal deformity caused by AS could be categorized into four patterns. APSO proved to be a feasible and effective procedure for correction of Pattern I to III patients. Coronal deformity pattern, apex location, sagittal profile of lumbar spine and preoperative hip function should be considered for osteotomy level selection in APSO.
评估强直性脊柱炎(AS)继发的冠状面畸形的不同模式,提出相关的治疗策略,并评估不对称性经椎弓根截骨术(APSO)的疗效。
冠状面畸形定义为冠状面 Cobb 角超过 20°或冠状面平衡距离(CBD)超过 3 cm。我们纳入了 65 例连续的伴有冠状面和矢状面畸形的 AS 患者,这些患者均接受了 PSO。平均随访时间为 40.4 个月。影像学评估包括冠状面 Cobb 角和 CBD。此外,矢状面参数用于评估后凸矫正的幅度和维持情况。
根据曲线特征,AS 引起的冠状面畸形包括四种不同的影像学模式:模式 I:腰椎侧凸;模式 II:胸腰椎 C 形曲线;模式 III:躯干移位但无主要曲线;模式 IV:胸上段脊柱侧凸。对于模式 I 至 III 的患者进行 APSO,而对于模式 IV 的患者进行常规 PSO。65 例患者的所有矢状面参数均显著改善,末次随访时无明显矫正丢失。此外,59 例 APSO 治疗的患者中,冠状面失平衡得到了显著和持续的矫正。4 例患者发生杆断裂,1 例患者行翻修手术。
根据影像学表现,AS 引起的冠状面畸形可分为四种类型。APSO 被证明是一种可行且有效的治疗模式 I 至 III 患者的方法。冠状面畸形模式、顶点位置、腰椎矢状面形态和术前髋关节功能应考虑用于 APSO 的截骨水平选择。