Sporer Elisabeth M, Schilling Christoph, Tait Robert J, Giurea Alexander, Grupp Thomas M
Aesculap AG, Research & Development, Tuttlingen, Germany.
Medical Department, Ludwig Maximilians University Munich, Munich, Germany.
PLoS One. 2024 Jun 13;19(6):e0305387. doi: 10.1371/journal.pone.0305387. eCollection 2024.
Pain at the tip of the stem of a knee prosthesis (End-of-Stem Pain) is a common problem in revision total knee arthroplasty (TKA). It may be caused by a problematic interaction between stem and bone, but the exact biomechanical correlate is still unknown. On top of this, there is no biomechanical study investigating End-of-Stem Pain at the distal femur using human specimens. Aim of this study was to find out whether the implantation of a revision total knee implant leads to high femoral surface strains at the tip of the stem, which the authors expect to be the biomechanical correlate of End-of-Stem Pain. We implanted 16 rotating hinge knee implants into 16 fresh-frozen human femora using the hybrid fixation technique and comparing two reaming protocols. Afterwards, surface strains on these femora were measured under dynamic load in two different load scenarios (climbing stairs and chair rising) using digital image correlation (DIC) and fracture patterns after overcritical load were analysed. Peak surface strains were found at the tip of the stem in several measurements in both load scenarios. There were no significant differences between the two compared groups (different trial sizes) regarding surface strains and fracture patterns. We conclude that implantation of a long intramedullary stem in revision TKA can lead to high surface strains at the tip of the stem that may be the correlate of femoral End-of-Stem Pain. This finding might allow for a targeted development of future stem designs that can lead to lower surface strains and therefore might reduce End-of-Stem Pain. Digital Image Correlation proved valid for the measurement of surface strains and can be used in the future to test new stem designs in vitro.
膝关节假体柄末端疼痛(柄末端疼痛)是翻修全膝关节置换术(TKA)中常见的问题。它可能是由柄与骨之间存在问题的相互作用引起的,但确切的生物力学关联仍不清楚。除此之外,尚无使用人体标本对股骨远端柄末端疼痛进行研究的生物力学研究。本研究的目的是确定翻修全膝关节假体的植入是否会导致柄末端股骨表面应变过高,作者认为这是柄末端疼痛的生物力学关联。我们采用混合固定技术将16个旋转铰链膝关节假体植入16个新鲜冷冻的人体股骨中,并比较两种扩髓方案。之后,在两种不同的负荷场景(爬楼梯和从椅子上起身)下,使用数字图像相关技术(DIC)测量这些股骨的表面应变,并分析超临界负荷后的骨折模式。在两种负荷场景下的多次测量中,均在柄末端发现了峰值表面应变。在表面应变和骨折模式方面,两个比较组(不同试验尺寸)之间没有显著差异。我们得出结论,在翻修TKA中植入长髓内柄可导致柄末端表面应变过高,这可能是股骨柄末端疼痛的关联因素。这一发现可能有助于有针对性地开发未来的柄设计,从而降低表面应变,进而可能减少柄末端疼痛。数字图像相关技术被证明可有效测量表面应变,未来可用于体外测试新的柄设计。