Ren Xuefeng Mm Mm Mm, Shen Lianqiang, Zhu Ming, Li Guogang
Altern Ther Health Med. 2024 Jun 14.
To investigate the clinical effects of new fiberoptic cholangioscopy-guided percutaneous transhepatic choledochoscope lithotomy (PTCSL) combined with dual-frequency laser lithotripsy for the treatment of intractable hepatolithiasis.
Eighty patients with intractable hepatolithiasis who received treatment in the Second Hospital Affiliated to Zhejiang University School of Medicine from December 2020 to December 2022 were grouped according to the surgical methods. Forty-two patients who received hepatectomy were divided into the control group, 38 patients who received new fiber-optic choledochoscope-guided PTCSL combined with dual-frequency laser lithotripsy were divided into the observation group, and the treatment results of the two groups were compared.
The operation time, postoperative pain duration, and hospital stay of the observation group were significantly shorter than those of the control group, and intraoperative bleeding was significantly lower than that of the control group, with statistically significant differences (P < .05). Seven days after surgery, the total bilirubin (TBIL), alanine aminotransferase (ALT), and albumin (ALB) levels in the observation group were significantly lower than those in the control group (P < .05). The stone residual rate of 7.89% in the observation group was significantly lower than that of 26.19% in the control group (χ2=4.625, P < .05). The difference in biliary bleeding rate between the two groups was not statistically significant (χ2=0.427, P > .05).
Overall results of new fiber-optic choledochoscope-guided PTCSL combined with dual-frequency laser lithotripsy for the treatment of intractable hepatolithiasis.
探讨新型纤维胆道镜引导下经皮经肝胆道镜取石术(PTCSL)联合双频激光碎石术治疗难愈性肝内胆管结石的临床疗效。
选取2020年12月至2022年12月在浙江大学医学院附属第二医院接受治疗的80例难愈性肝内胆管结石患者,根据手术方式进行分组。42例行肝切除术的患者分为对照组,38例行新型纤维胆道镜引导下PTCSL联合双频激光碎石术的患者分为观察组,比较两组的治疗效果。
观察组手术时间、术后疼痛持续时间及住院时间均明显短于对照组,术中出血量明显少于对照组,差异有统计学意义(P < 0.05)。术后7天,观察组总胆红素(TBIL)、谷丙转氨酶(ALT)及白蛋白(ALB)水平明显低于对照组(P < 0.05)。观察组结石残留率为7.89%,明显低于对照组的26.19%(χ2 = 4.625,P < 0.05)。两组胆道出血率差异无统计学意义(χ2 = 0.427,P > 0.05)。
新型纤维胆道镜引导下PTCSL联合双频激光碎石术治疗难愈性肝内胆管结石的总体效果。