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经皮经肝胆道硬镜碎石术与传统经皮经肝胆道镜手术治疗肝内胆管结石的比较

Comparison Between Percutaneous Transhepatic Rigid Cholangioscopic Lithotripsy and Conventional Percutaneous Transhepatic Cholangioscopic Surgery for Hepatolithiasis Treatment.

作者信息

Wang Ping, Sun Beiwang, Huang Binyuan, Xie Jiafen, Liu Yanmin, Zhu Canhua, Ye Chen, Zhou Zixuan

机构信息

Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong Province, China.

出版信息

Surg Laparosc Endosc Percutan Tech. 2016 Feb;26(1):54-9. doi: 10.1097/SLE.0000000000000222.

Abstract

BACKGROUND

Percutaneous transhepatic cholangioscopy (PTCS) is one option for treating hepatolithiasis without surgical resection. This approach can use conventional biliary drainage methods over a long period, but a shorter procedure needs to be evolved.

OBJECTIVE

To evaluate the short-term and the long-term therapeutic outcomes of percutaneous transhepatic cholangioscopic lithotripsy (PTCSL) in comparison with conventional PTCS.

METHODS

In this retrospective study, 118 patients with hepatolithiasis were enrolled who underwent treatment in our hospital between March 2007 and July 2014. About 67 of them received PTCSL and the remaining 51 patients received conventional PTCS. Preoperative data, surgical operation-related records, the postoperative therapeutic effect, and the long-term hepatolithiasis recurrence rate were collected for comparison between the 2 groups.

RESULTS

The age, sex, and surgical history were similar between the 2 groups, but there was a significant difference in the Child-Pugh score, with more grade 3 patients in the PTCS group (P=0.002). However, the operation time, intraoperative blood infusion, and the blood loss were similar between the 2 groups. The final clearance ratio of calculus in the PTCSL group was significantly better than in the PTCS group after multivariate analysis (P=0.021; OR=0.201; 95% CI, 0.051-0.785). Calculus recurrence was 9% (PTCSL) and 22% (PTCS). The postoperative hospital stay was significantly shorter in the PTCSL group (P=0.001; OR=1.337; 95% CI, 1.132-1.58).

CONCLUSIONS

PTCSL was a satisfactory therapeutic option for hepatolithiasis treatment, with less operation time and a superior long-term therapeutic effect compared with conventional PTCS.

摘要

背景

经皮经肝胆道镜检查(PTCS)是一种无需手术切除治疗肝内胆管结石的方法。这种方法可以长期使用传统的胆道引流方法,但需要改进更短的手术流程。

目的

评估经皮经肝胆道镜碎石术(PTCSL)与传统PTCS相比的短期和长期治疗效果。

方法

在这项回顾性研究中,纳入了2007年3月至2014年7月在我院接受治疗的118例肝内胆管结石患者。其中约67例接受了PTCSL,其余51例患者接受了传统PTCS。收集术前数据、手术相关记录、术后治疗效果以及长期肝内胆管结石复发率,用于两组之间的比较。

结果

两组患者的年龄、性别和手术史相似,但Child-Pugh评分存在显著差异,PTCS组3级患者更多(P=0.002)。然而,两组之间的手术时间、术中输血和失血量相似。多因素分析后,PTCSL组结石最终清除率明显优于PTCS组(P=0.021;OR=0.201;95%CI,0.051-0.785)。结石复发率分别为9%(PTCSL)和22%(PTCS)。PTCSL组术后住院时间明显缩短(P=0.001;OR=1.337;95%CI,1.132-1.58)。

结论

PTCSL是治疗肝内胆管结石的一种满意的治疗选择,与传统PTCS相比,手术时间更短,长期治疗效果更佳。

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