Department of Ophthalmology, Jiangxi Yingtan People's Hospital, Jiangxi Province, China.
Department of Ophthalmology, The Second People's Hospital of Guangdong Foshan, China.
Photodiagnosis Photodyn Ther. 2024 Aug;48:104237. doi: 10.1016/j.pdpdt.2024.104237. Epub 2024 Jun 12.
To report the use of anterior segment optical coherence tomography (AS-OCT) for superficial keratectomy (SK) in anterior corneal opacity.
The characteristics of 43 eyes (39 patients) with various lesions responsible for anterior corneal opacity were included in this retrospective non-comparative study. AS-OCT was performed on all eyes before surgery. The thickness of corneal opacity and the underlying healthy stroma were measured. SK was performed on each individual.
Four types of anterior corneal opacity were evaluated, including corneal degeneration (26/43), Reis-Bücklers corneal dystrophy (8/43), alkali burn (1/43) and corneal tumors (8/43). Based on AS-OCT images, all eyes showed abnormal hyper-reflective signals in the superficial cornea to less than one-third of the normal corneal thickness in the deepest corneal opacity. All 43 eyes underwent an SK procedure. In addition, 1 eye with alkali burns and 7 eyes with corneal tumors were combined with amniotic membrane transplantation. All eyes restored transparency without significant complications.
AS-OCT is a valuable method for objective preoperative and noninvasive assessments of anterior corneal opacities and is useful for guiding SK.
报告应用眼前节光学相干断层扫描（AS-OCT）对角膜前部混浊行浅层角膜切除术（SK）的情况。
本回顾性非对照研究纳入了 43 只眼（39 例患者），这些眼均因各种病变导致角膜前部混浊。所有眼术前均行 AS-OCT 检查，测量角膜混浊的厚度和其下正常基质的厚度。对每只眼分别行 SK。
评估了 4 种类型的角膜前部混浊，包括角膜变性（26/43）、Reis-Bücklers 角膜营养不良（8/43）、碱烧伤（1/43）和角膜肿瘤（8/43）。根据 AS-OCT 图像，所有眼在最深部角膜混浊中均显示浅层角膜异常的高反射信号，范围不到正常角膜厚度的 1/3。所有 43 只眼均行 SK 术，其中 1 只碱烧伤眼和 7 只角膜肿瘤眼联合行羊膜移植。所有眼均恢复透明，无明显并发症。
AS-OCT 是一种对角膜前部混浊进行客观术前和非侵入性评估的有价值方法，有助于 SK 术的指导。
