Maeda Tetsuro, Connolly Margaret, Modrak Joseph, Perillo Irene
Division of Pulmonary and Critical Care Medicine, University of Rochester Medical Center, 601 Elmwood Ave, Rochester, NY, 14642, United States.
Respir Med Case Rep. 2024 May 27;50:102043. doi: 10.1016/j.rmcr.2024.102043. eCollection 2024.
Metastatic pulmonary calcification (MPC) is a metabolic disorder characterized by an ectopic deposition of calcium in the lung parenchyma, prevalent in patients with chronic kidney disease. A combination of parenchymal lung abnormalities on high resolution chest computed tomography (CT) and pulmonary radiotracer uptake in Tc-methyl diphosphate (MDP) bone scintigraphy can establish diagnosis of MPC. We herein present a case of MPC with documented stability of chest CT abnormalities after renal transplant. We also describe novel findings of diffuse pulmonary uptake of F-sodium fluoride, a calcium-avid radiotracer, in positron emission tomography (PET)/CT performed in the same patient.
转移性肺钙化(MPC)是一种代谢紊乱疾病,其特征是钙在肺实质中异位沉积,在慢性肾病患者中很常见。高分辨率胸部计算机断层扫描(CT)显示的肺实质异常与锝-亚甲基二膦酸盐(MDP)骨闪烁显像中的肺部放射性示踪剂摄取相结合,可确诊MPC。我们在此报告一例肾移植后胸部CT异常表现稳定的MPC病例。我们还描述了在同一患者进行的正电子发射断层扫描(PET)/CT中,新型钙亲和放射性示踪剂氟代氟化钠在肺部弥漫性摄取的新发现。