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巨细胞病毒阳性肾源性腺瘤导致的急性肾移植术后肾后性肾功能障碍——病例报告及文献复习

Acute post-renal kidney graft dysfunction due to cytomegalovirus-positive nephrogenic adenoma-case report and review of the literature.

作者信息

Hosek Nicola, Montani Matteo, Mani Laila-Yasmin

机构信息

Department of Medicine, Division of Nephrology and Dialysis, Kantonsspital Graubünden, Chur, Switzerland.

Department of Nephrology and Hypertension, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

出版信息

Front Med (Lausanne). 2024 May 29;11:1394028. doi: 10.3389/fmed.2024.1394028. eCollection 2024.

DOI:10.3389/fmed.2024.1394028
PMID:38873192
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11175655/
Abstract

Tissue-invasive cytomegalovirus (CMV) disease represents a well-recognized complication after kidney transplantation. However, direct involvement of the urogenital tract and CMV-ureteritis occur less frequently. Nephrogenic adenomas are benign lesions of the urinary tract preferentially reported in kidney transplant recipients. We herein report a second case of a 33-year-old male kidney transplant recipient with acute post-renal allograft dysfunction due to CMV-positive ureteral nephrogenic adenoma. A causal connection might be suspected but remains to be proven.

摘要

组织侵袭性巨细胞病毒(CMV)病是肾移植后一种公认的并发症。然而,泌尿生殖道直接受累及CMV输尿管炎的情况较少见。肾源性腺瘤是尿路的良性病变,在肾移植受者中报道较多。我们在此报告第二例33岁男性肾移植受者,因CMV阳性输尿管肾源性腺瘤导致急性肾移植术后肾功能不全。可能怀疑存在因果关系,但仍有待证实。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1908/11175655/a3fe225faf06/fmed-11-1394028-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1908/11175655/db1666f9bcf0/fmed-11-1394028-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1908/11175655/ecc09387f53b/fmed-11-1394028-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1908/11175655/209d4c17ae65/fmed-11-1394028-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1908/11175655/a7b2abc61209/fmed-11-1394028-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1908/11175655/a3fe225faf06/fmed-11-1394028-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1908/11175655/db1666f9bcf0/fmed-11-1394028-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1908/11175655/ecc09387f53b/fmed-11-1394028-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1908/11175655/209d4c17ae65/fmed-11-1394028-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1908/11175655/a7b2abc61209/fmed-11-1394028-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1908/11175655/a3fe225faf06/fmed-11-1394028-g005.jpg

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本文引用的文献

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Bacterial and Viral Infection and Sepsis in Kidney Transplanted Patients.肾移植患者的细菌和病毒感染及脓毒症
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Nephrogenic Adenoma of the Urinary Bladder after Kidney Transplantation: Long-Term Follow-Up.肾移植术后膀胱源性腺瘤:长期随访
Case Rep Transplant. 2020 Oct 16;2020:8831966. doi: 10.1155/2020/8831966. eCollection 2020.
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The Third International Consensus Guidelines on the Management of Cytomegalovirus in Solid-organ Transplantation.《实体器官移植中巨细胞病毒管理的第三次国际共识指南》。
Transplantation. 2018 Jun;102(6):900-931. doi: 10.1097/TP.0000000000002191.
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Nephrogenic Adenoma Complicating Renal Transplantation: A Case Report and Discussion.肾移植并发肾源性腺瘤:一例报告及讨论
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Nephrogenic Adenoma: Clinical Features, Management, and Diagnostic Pitfalls.肾源性腺瘤:临床特征、治疗及诊断陷阱
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BK polyomavirus-infected nephrogenic adenoma of the urinary bladder in a renal transplant recipient: A case report.肾移植受者膀胱BK多瘤病毒感染所致肾源性腺瘤:一例报告
Pathol Res Pract. 2015 Sep;211(9):697-701. doi: 10.1016/j.prp.2015.06.006. Epub 2015 Jun 11.
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Cytomegalovirus immune evasion by perturbation of endosomal trafficking.巨细胞病毒通过干扰内体运输实现免疫逃逸。
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Nephrogenic adenoma of the urinary bladder: a report of three cases and a review of the literature.
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