数字与非数字健康干预措施改善孕妇铁补充情况：一项系统评价与荟萃分析
Digital versus non-digital health interventions to improve iron supplementation in pregnant women: a systematic review and meta-analysis.
作者信息
Shao Yu, Meng Chao, Liang Ying-Zhi
机构信息
Department of Maternal Health, Beijing Haidian Maternal and Child Health Hospital, Beijing, China.
出版信息
Front Med (Lausanne). 2024 May 30;11:1375622. doi: 10.3389/fmed.2024.1375622. eCollection 2024.
OBJECTIVE
To investigate the effects of digital health interventions for improving adherence to oral iron supplementation in pregnant women.
LITERATURE SEARCH
Five databases were searched from their inception to October 2023 with no date restrictions.
STUDY SELECTION
Randomized controlled trials (RCTs) that assessed the effects of digital health interventions on adherence to oral iron supplementation (e.g., tablets and capsules) compared to non-digital health interventions for pregnant women were eligible.
DATA SYNTHESIS
We calculated standardized mean differences (SMDs) and mean differences (MDs) with 95% confidence intervals (CIs) for continuous variables using the inverse variance method. We calculated odds ratios (OR) with 95%CI for categorical variables using the Mantel-Haenszel model. The certainty of the evidence was assessed using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach. The risk of bias of the included RCTs was assessed using the Cochrane risk of bias tool 2.0.
RESULTS
Ten trials with 1,633 participants were included. Based on 7 trials, digital health interventions can improve objective adherence rate comparing with non-digital health interventions (1,289 participants, OR = 4.07 [2.19, 7.57], < 0.001, I = 69%) in pregnant women. Digital health interventions can improve subjective adherence behavior comparing with non-digital health interventions (3 trials, 434 participants, SMD = 0.82 [0.62, 1.01], < 0.001, I = 0%) in pregnant women. Based on 3 trials, digital health interventions can improve tablets consumption comparing with non-digital health interventions (333 participants, SMD = 1.00 [0.57, 1.42], < 0.001, I = 66%) in pregnant women. Digital health interventions can improve hemoglobin level comparing with non-digital health interventions (7 trials, 1,216 participants, MD = 0.59 [0.31, 0.88], < 0.001, I = 93%) in pregnant women.
CONCLUSION
Digital health interventions were effective at improving adherence to oral iron supplementation and hemoglobin levels in pregnant women.
目的
探讨数字健康干预对提高孕妇口服铁补充剂依从性的效果。
文献检索
检索了五个数据库，从建库至2023年10月，无日期限制。
研究选择
符合条件的为随机对照试验（RCT），该试验评估数字健康干预与非数字健康干预相比对孕妇口服铁补充剂（如片剂和胶囊）依从性的影响。
数据合成
对于连续变量，我们使用逆方差法计算标准化均数差（SMD）和均数差（MD）以及95%置信区间（CI）。对于分类变量，我们使用Mantel-Haenszel模型计算比值比（OR）及95%CI。使用推荐分级评估、制定和评价（GRADE）方法评估证据的确定性。使用Cochrane偏倚风险工具2.0评估纳入的RCT的偏倚风险。
结果
纳入了10项试验，共1633名参与者。基于7项试验，与非数字健康干预相比，数字健康干预可提高孕妇的客观依从率（1289名参与者，OR = 4.07 [2.19, 7.57]，P < 0.001，I² = 69%）。与非数字健康干预相比，数字健康干预可改善孕妇的主观依从行为（3项试验，434名参与者，SMD = 0.82 [0.62, 1.01]，P < 0.001，I² = 0%）。基于3项试验，与非数字健康干预相比，数字健康干预可提高孕妇的片剂服用量（333名参与者，SMD = 1.00 [0.57, 1.42]，P < 0.001，I² = 66%）。与非数字健康干预相比，数字健康干预可提高孕妇的血红蛋白水平（7项试验，1216名参与者，MD = 0.59 [0.31, 0.88]，P < 0.001，I² = 93%）。
结论
数字健康干预在提高孕妇口服铁补充剂的依从性和血红蛋白水平方面是有效的。
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