Adu D, Michael J, Vlassis T, McMaster P
Proc Eur Dial Transplant Assoc Eur Ren Assoc. 1985;21:998-1001.
Out of 58 consecutive cadaveric renal allograft recipients whose initial immunosuppression was cyclosporine (Cys) and prednisolone, 18 were converted to prednisolone and azathioprine. Of these all four patients converted because of rejection lost their grafts. Renal function improved in seven patients converted because of nephrotoxicity and in six out of seven patients converted for miscellaneous reasons. Out of five patients converted electively at three months, one died of infection and three developed acute rejection episodes.
在58例初始免疫抑制采用环孢素（Cys）和泼尼松龙的连续尸体肾移植受者中，18例改为泼尼松龙和硫唑嘌呤治疗。在这些患者中，因排斥反应而转换治疗的4例患者均失去了移植肾。因肾毒性而转换治疗的7例患者肾功能得到改善，因其他原因转换治疗的7例患者中有6例肾功能改善。在3个月时选择性转换治疗的5例患者中，1例死于感染，3例发生急性排斥反应。
