甲状腺癌患者的肺叶切除术：智利一家三级中心的经验。
Lobectomy in patients with differentiated thyroid cancer: experience of a Chilean tertiary center.
机构信息
Department of Endocrinology, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
CETREN-UC, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
出版信息
Endocrine. 2024 Nov;86(2):692-698. doi: 10.1007/s12020-024-03905-1. Epub 2024 Jun 14.
PURPOSE
Thyroid lobectomy (TL) is an appropriate treatment for up to 4 cm intrathyroidal differentiated thyroid cancer (DTC). There is scarce data regarding TL outside first-world centers. Our aim is to report a cohort of patients with DTC treated with TL in Chile.
METHODS
We included DTC patients treated with TL, followed for at least 6 months, characterized their clinicopathological features and classified their risk of recurrence and response to treatment.
RESULTS
Eighty-two patients followed for a median of 2.3 years (0.5-7.0). Seventy-three (89%) patients had papillary, 8 (9.8%) follicular and 1 (1.2%) high-grade DTC. The risk of recurrence was low in 56 (68.3%) and intermediate in 26 (31.7%). Eight (9.8%) patients required early completion thyroidectomy and radioiodine. At last follow-up, 52 (70.3%) had excellent, 19 (25.7%) had indeterminate, and 1 (1.4%) had structural incomplete response.
CONCLUSION
In a developing country, TL is an adequate option for appropriately selected DTC patients.
目的
甲状腺叶切除术（TL）是治疗最大直径为 4cm 的甲状腺内分化型甲状腺癌（DTC）的合适方法。关于非发达国家中心的 TL 数据很少。我们的目的是报告在智利接受 TL 治疗的 DTC 患者的队列。
方法
我们纳入了至少随访 6 个月、接受 TL 治疗的 DTC 患者，对其临床病理特征进行了描述，并对其复发风险和治疗反应进行了分类。
结果
82 例患者的中位随访时间为 2.3 年（0.5-7.0）。73 例（89%）患者为乳头状，8 例（9.8%）为滤泡状，1 例（1.2%）为高级别 DTC。56 例（68.3%）患者复发风险低，26 例（31.7%）患者复发风险中。8 例（9.8%）患者需要早期完成甲状腺切除术和放射性碘治疗。末次随访时，52 例（70.3%）患者有极好的反应，19 例（25.7%）患者有不确定的反应，1 例（1.4%）患者有结构不完全反应。
结论
在发展中国家，TL 是为适当选择的 DTC 患者提供的一种合适的选择。
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