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腹腔镜肝切除术中灾难性二氧化碳栓塞的先兆:一例报告。

A portent of catastrophic carbon dioxide embolism in laparoscopic hepatectomy: A case report.

机构信息

Department of Anesthesiology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China.

Department of Anesthesiology, Haining People's Hospital, Haining, Zhejiang Province, China.

出版信息

Medicine (Baltimore). 2024 Jun 14;103(24):e38468. doi: 10.1097/MD.0000000000038468.

DOI:10.1097/MD.0000000000038468
PMID:38875434
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11175889/
Abstract

INTRODUCTION

Laparoscopic hepatectomy (LH) poses a high risk of carbon dioxide embolism due to extensive hepatic transection, long surgery duration, and dissection of the large hepatic veins or vena cava.

PATIENT CONCERNS

A 65-year-old man was scheduled to undergo LH. Following intraperitoneal carbon dioxide (CO2) insufflation and hepatic portal occlusion, the patient developed severe hemodynamic collapse accompanied by a decrease in the pulse oxygen saturation (SpO2).

DIAGNOSIS

Although a decrease in end-tidal carbon dioxide (ETCO2) was not observed, CO2 embolism was still suspected because of the symptoms.

INTERVENTIONS AND OUTCOMES

The patient was successfully resuscitated after the immediate discontinuation of CO2 insufflation and inotrope administration. CO2 embolism must always be suspected during laparoscopic surgery whenever sudden hemodynamic collapse associated with decreased pulse oxygen saturation occurs, regardless of whether ETCO2 changes. Instant arterial blood gas analysis is imperative, and a significant difference between PaCO2 and ETCO2 is indicative of carbon dioxide embolism.

CONCLUSION

Instant arterial blood gas analysis is imperative, and a significant difference between PaCO2 and ETCO2 is indicative of carbon dioxide embolism.

摘要

介绍

由于广泛的肝切除术、手术时间长以及大肝静脉或腔静脉的分离,腹腔镜肝切除术 (LH) 存在二氧化碳栓塞的高风险。

患者关注

一位 65 岁男性计划接受 LH。在腹腔内二氧化碳 (CO2) 充气和肝门阻断后,患者出现严重的血流动力学崩溃,伴有脉搏血氧饱和度 (SpO2) 下降。

诊断

尽管未观察到呼气末二氧化碳 (ETCO2) 下降,但由于出现症状,仍怀疑发生 CO2 栓塞。

干预和结果

立即停止 CO2 充气和使用正性肌力药后,患者成功复苏。无论 ETCO2 是否发生变化,只要在腹腔镜手术中发生与脉搏血氧饱和度降低相关的突然血流动力学崩溃,都应始终怀疑 CO2 栓塞。即时动脉血气分析至关重要,PaCO2 和 ETCO2 之间存在显著差异提示存在二氧化碳栓塞。

结论

即时动脉血气分析至关重要,PaCO2 和 ETCO2 之间存在显著差异提示存在二氧化碳栓塞。

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本文引用的文献

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Ventricular tachycardia and acute heart failure induced by atropine in the treatment of bradycardia: A case report and literature review.阿托品治疗心动过缓致室性心动过速和急性心力衰竭 1 例并文献复习
Medicine (Baltimore). 2023 Aug 25;102(34):e34775. doi: 10.1097/MD.0000000000034775.
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An abrupt decrease in arterial blood pressure may predict a high level carbon dioxide embolism in retroperitoneoscopic surgery: case report and a literature review.动脉血压突然下降可能预示着后腹腔镜手术中存在高碳酸血症栓塞:病例报告及文献复习。
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Carbon dioxide embolism during posterior retroperitoneal adrenalectomy.后腹膜肾上腺切除术中的二氧化碳栓塞
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Carbon dioxide embolism with severe hypotension as an initial symptom during laparoscopy: a case report.二氧化碳栓塞致严重低血压:腹腔镜术中首发的 1 例病例报告。
J Int Med Res. 2021 Apr;49(4):3000605211004765. doi: 10.1177/03000605211004765.
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Automatic detection of venous air embolism using transesophageal echocardiography in patients undergoing neurological surgery in the semi-sitting position: a pilot study.经食管超声心动图在半坐体位行神经外科手术患者中自动检测静脉空气栓塞的初步研究。
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