Key Laboratory of Karst Georesources and Environment, College of Resource and Environmental Engineering, Guizhou University, Guiyang, P. R. China.
Plant Protection and Plant Inspection Station of Guizhou Province, Guiyang, Guizhou, P. R. China.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2024 Aug;41(8):914-922. doi: 10.1080/19440049.2024.2357351. Epub 2024 Jun 14.
() is a unique, edible, medicinal fruit rich in vitamin C found in Southwest China. Triadimefon (TDF) is a triazole fungicide that is widely used to control powdery mildew in . To assess the safety of TDF in , an LC-MS/MS method was developed for the simultaneous quantification of TDF and its major metabolite, triadimenol (TDN) in Both TDF and TDN showed high correlation coefficients (>0.999) for the solvent- and matrix-matched calibrations. The recovery rates of TDF and TDN in ranged from 90.18% to 100.42%, with a relative standard deviation () of 1.25%-9.22%. The limit of quantification () was 0.01 mg·kg. The half-life of TDF in was between 2.74 and 3.07 days, with terminal residues ranging from < to 1.84 mg·kg. Recommended maximum residue limits (s) and safe pre-harvest intervals (s) for TDF in were 0.5 mg·kg and 21 days, respectively. This study provides essential data for TDF's safe and judicious use in production.
() 是一种独特的、可食用的、药用水果，富含维生素 C，产于中国西南地区。三唑酮 (TDF) 是一种三唑类杀菌剂，广泛用于防治 中的白粉病。为评估 TDF 在 中的安全性，建立了一种 LC-MS/MS 方法，用于同时定量分析 中的 TDF 及其主要代谢物三唑醇 (TDN)。TDF 和 TDN 在溶剂和基质匹配校准中均表现出高相关性系数 (>0.999)。TDF 和 TDN 在 中的回收率在 90.18%至 100.42%之间，相对标准偏差 () 在 1.25%-9.22%之间。定量限 () 为 0.01 mg·kg。TDF 在 中的半衰期在 2.74 至 3.07 天之间，终端残留量在 < 至 1.84 mg·kg 之间。在 中，TDF 的建议最大残留限量 (s) 和安全收获前间隔 (s) 分别为 0.5 mg·kg 和 21 天。本研究为 TDF 在 生产中的安全合理使用提供了重要数据。
