Breast Unit, Western General Hospital, Edinburgh, EH4 2XU, Scotland, UK.
Breast Unit, Western General Hospital, Edinburgh, EH4 2XU, Scotland, UK.
Cancer Treat Res Commun. 2024;40:100821. doi: 10.1016/j.ctarc.2024.100821. Epub 2024 May 24.
The landscape of breast reconstruction has changed significantly with a shift in focus to include the restoration of a patient's quality of life after cancer. Reconstructive options can be divided into alloplastic (implant based) and autologous (tissue based). This paper aims to provide a current educational summary regarding implant-based reconstruction after breast cancer surgery and review the current literature.
A review of the literature was conducted utilising standard PRISMA flowchart. Databases searched included Pubmed, EMBASE, and MEDLINE.
Current practice is explored within the text, including types of implants, indications, and surgical approaches. Heterogenous cohorts, surgical technique variation, and selection bias can make comparison of the literature challenging. The major evidence reviews of implant-based reconstruction topics are discussed including, ADM use, radiotherapy, and complications. Despite the benefits of autologous reconstruction, implant-based techniques still represent a significant proportion of reconstructive breast procedures. However, implant-reconstruction is not without its risks and limitations and, with such variety in practice, there remains a lack of high-quality evidence guiding practice. Most importantly, patients need to be counselled about the pros and cons of each choice, particularly with the increasing utilisation of radiotherapy post-reconstruction. Ultimately, the patient and surgeon should reach a decision in full knowledge of the risks and potential outcomes.
Further research is required into implant-based reconstructive therapy, which will allow a greater consensus for management and a pathway for both surgeons and patients.
随着关注焦点转移到癌症患者生活质量的恢复,乳房重建的格局发生了重大变化。重建方案可分为假体(基于植入物)和自体(基于组织)。本文旨在提供关于乳腺癌手术后基于植入物的重建的当前教育性总结,并回顾当前的文献。
利用标准 PRISMA 流程图对文献进行了回顾。搜索的数据库包括 Pubmed、EMBASE 和 MEDLINE。
本文探讨了当前的实践,包括植入物的类型、适应证和手术方法。异质队列、手术技术的变化和选择偏倚使得文献比较具有挑战性。讨论了关于植入物重建主题的主要证据综述,包括 ADM 的使用、放疗和并发症。尽管自体重建具有优势,但基于植入物的技术仍然代表了很大一部分重建乳房手术。然而,植入物重建并非没有风险和限制,而且由于实践的多样性,缺乏指导实践的高质量证据。最重要的是,患者需要充分了解每种选择的利弊,特别是在重建后放疗的应用越来越多的情况下。最终,患者和外科医生应在充分了解风险和潜在结果的情况下做出决定。
需要进一步研究基于植入物的重建治疗,以便为管理达成更大共识,并为外科医生和患者提供一条途径。