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头孢唑林接种物效应对耐甲氧西林金黄色葡萄球菌临床分离株的影响。

Cefazolin inoculum effect in methicillin-susceptible Staphylococcus aureus clinical isolates.

机构信息

Department of Bacteriology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan; Department of Medical Laboratory Science, Okayama University Graduate School of Health Sciences, Okayama, Japan.

Department of Medical Laboratory Science, Okayama University Graduate School of Health Sciences, Okayama, Japan.

出版信息

Diagn Microbiol Infect Dis. 2024 Sep;110(1):116399. doi: 10.1016/j.diagmicrobio.2024.116399. Epub 2024 Jun 10.

Abstract

We investigated the prevalence and characteristics of Cefazolin inoculum effect (CInE) among clinical MSSA isolates in Japan. Although 35.5 % (39 isolates) were positive for the blaZ gene, none met the phenotypic criteria for CInE. Our findings suggested a very low prevalence of CInE among MSSA isolates in our clinical setting.

摘要

我们研究了日本临床分离的金黄色葡萄球菌中头孢唑林接种物效应(CInE)的流行率和特征。虽然 blaZ 基因阳性率为 35.5%(39 株),但没有一株符合 CInE 的表型标准。我们的研究结果表明,在我们的临床环境中,MSSA 分离株中 CInE 的发生率非常低。

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