Stuart-Macadam P
Am J Phys Anthropol. 1985 Apr;66(4):391-8. doi: 10.1002/ajpa.1330660407.
Porotic hyperostosis is currently considered to be one of several stress markers available for assessing the health and nutritional status of past human populations. The present study questions one of the basic assumptions underlying its use; that is, that the occurrence of porotic hyperostosis in an individual represents an episode of anemia that was current or had occurred within a relatively short period prior to death. A synthesis of data from a Romano-British site Poundbury Camp, anthropological and clinical studies, and information on bone physiology suggests that lesions of porotic hyperostosis seen in adults are most probably representative of a childhood episode of anemia. Lesions seen in adults are the result of bone changes occurring in the growth period that have not undergone complete remodelling. This viewpoint has implications for future interpretation of data on porotic hyperostosis obtained from skeletal collections.
多孔性骨质增生目前被认为是可用于评估过去人类群体健康和营养状况的几种应激指标之一。本研究对其使用背后的一个基本假设提出了质疑；也就是说，个体中出现多孔性骨质增生代表着在死亡前相对较短的时期内当前或已经发生的贫血发作。对来自罗马 - 不列颠遗址庞德伯里营地的数据、人类学和临床研究以及骨骼生理学信息的综合分析表明，在成年人中看到的多孔性骨质增生病变很可能代表儿童时期的贫血发作。成年人中看到的病变是生长期发生的骨骼变化的结果，这些变化尚未完全重塑。这一观点对未来从骨骼收藏中获得的多孔性骨质增生数据的解释具有启示意义。
