Suppr超能文献

在商用隐形眼镜上进行功能化水凝胶的光聚合增材制造

Vat photopolymerization printing of functionalized hydrogels on commercial contact lenses.

作者信息

Hisham Muhammed, Butt Haider

机构信息

Department of Mechanical and Nuclear Engineering, Khalifa University of Science and Technology, Abu Dhabi, 127788, UAE.

出版信息

Sci Rep. 2024 Jun 15;14(1):13860. doi: 10.1038/s41598-024-63846-7.

Abstract

Contact lenses are widely used for vision correction and cosmetic purposes. Smart contact lenses offer further opportunities as functionalized non-invasive devices capable of simultaneous vision correction, real-time health monitoring and patient specific drug delivery. Herein, a low-cost vat photopolymerization technique is developed for directly 3D printing functionalized structures on commercially available contact lenses. The process enables controlled deposition of functionalized hydrogels, in customizable patterns, on the commercial contact lens surface with negligible optical losses. Multi-functional contact lenses can also be 3D printed with multiple materials deposited at different regions of the contact lens. Herein, the functionalities of colour blindness correction and real-time UV monitoring are demonstrated, by employing three suitable dyes incorporated into 2-hydroxyethyl methacrylate (HEMA) hydrogel structures printed on contact lenses. The results suggest that 3D printing can pave the way towards simple production of low-cost patient specific smart contact lenses.

摘要

隐形眼镜被广泛用于视力矫正和美容目的。智能隐形眼镜作为一种功能化的非侵入性设备,能够同时进行视力矫正、实时健康监测和针对患者的药物递送,提供了更多机会。在此,开发了一种低成本的 vat 光聚合技术,用于在市售隐形眼镜上直接 3D 打印功能化结构。该工艺能够以可定制的图案将功能化水凝胶可控地沉积在商业隐形眼镜表面,且光学损失可忽略不计。多功能隐形眼镜也可以用多种材料 3D 打印,这些材料沉积在隐形眼镜的不同区域。在此,通过将三种合适的染料掺入打印在隐形眼镜上的甲基丙烯酸 2-羟乙酯(HEMA)水凝胶结构中,展示了色盲矫正和实时紫外线监测的功能。结果表明,3D 打印可为低成本的针对患者的智能隐形眼镜的简单生产铺平道路。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/16ab/11180191/55e331165392/41598_2024_63846_Fig1_HTML.jpg

相似文献

1
Vat photopolymerization printing of functionalized hydrogels on commercial contact lenses.
Sci Rep. 2024 Jun 15;14(1):13860. doi: 10.1038/s41598-024-63846-7.
2
3D Printing of Multimaterial Contact Lenses.
ACS Biomater Sci Eng. 2023 Jul 10;9(7):4381-4391. doi: 10.1021/acsbiomaterials.3c00175. Epub 2023 Jun 26.
4
3D Printed Contact Lenses.
ACS Biomater Sci Eng. 2021 Feb 8;7(2):794-803. doi: 10.1021/acsbiomaterials.0c01470. Epub 2021 Jan 19.
5
Microengineered poly(HEMA) hydrogels for wearable contact lens biosensing.
Lab Chip. 2020 Nov 10;20(22):4205-4214. doi: 10.1039/d0lc00446d.
6
Continuous Vat Photopolymerization for Optical Lens Fabrication.
Small. 2023 Oct;19(40):e2300517. doi: 10.1002/smll.202300517. Epub 2023 May 28.
7
Vat Photopolymerization 3D Printing of Hydrogels with Re-Adjustable Swelling.
Gels. 2023 Jul 25;9(8):600. doi: 10.3390/gels9080600.
8
Liquid-Phase Integrated 3D Printed Biological Lenses for Lamellar Corneal Substitute.
Adv Healthc Mater. 2023 Oct;12(27):e2300600. doi: 10.1002/adhm.202300600. Epub 2023 Sep 17.
10
Current Biomedical Applications of 3D-Printed Hydrogels.
Gels. 2023 Dec 21;10(1):8. doi: 10.3390/gels10010008.

引用本文的文献

本文引用的文献

2
Long-term stable wireless smart contact lens for robust digital diabetes diagnosis.
Biomaterials. 2023 Nov;302:122315. doi: 10.1016/j.biomaterials.2023.122315. Epub 2023 Sep 4.
3
3D Printing of Multimaterial Contact Lenses.
ACS Biomater Sci Eng. 2023 Jul 10;9(7):4381-4391. doi: 10.1021/acsbiomaterials.3c00175. Epub 2023 Jun 26.
4
Inkjet drug printing onto contact lenses: Deposition optimisation and non-invasive dose verification.
Int J Pharm X. 2022 Dec 20;5:100150. doi: 10.1016/j.ijpx.2022.100150. eCollection 2023 Dec.
5
6
A Review of Multi-Material 3D Printing of Functional Materials via Vat Photopolymerization.
Polymers (Basel). 2022 Jun 16;14(12):2449. doi: 10.3390/polym14122449.
7
Wearable Smart Contact Lenses for Continual Glucose Monitoring: A Review.
Front Med (Lausanne). 2022 Apr 4;9:858784. doi: 10.3389/fmed.2022.858784. eCollection 2022.
8
Challenges, Prospects, and Emerging Applications of Inkjet-Printed Electronics: A Chemist's Point of View.
Angew Chem Int Ed Engl. 2022 May 9;61(20):e202200166. doi: 10.1002/anie.202200166. Epub 2022 Mar 31.
9
Suppressing the Step Effect of 3D Printing for Constructing Contact Lenses.
Adv Mater. 2022 Jan;34(4):e2107249. doi: 10.1002/adma.202107249. Epub 2021 Dec 2.
10
Gold Nanocomposite Contact Lenses for Color Blindness Management.
ACS Nano. 2021 Mar 23;15(3):4870-4880. doi: 10.1021/acsnano.0c09657. Epub 2021 Feb 11.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验