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低钾型周期性瘫痪产妇行剖宫产的麻醉管理:病例报告及文献复习。

Anaesthetic management of a parturient with hypokalaemic periodic paralysis for caesarean section: A case report and review of the literature.

机构信息

Department of Anaesthesia, Gosford Hospital, Gosford, Australia.

出版信息

Anaesth Intensive Care. 2024 Jul;52(4):250-255. doi: 10.1177/0310057X231178840. Epub 2024 Jun 16.

Abstract

A 32-year-old multigravida woman, with known familial hypokalaemic periodic paralysis, underwent spinal anaesthesia for an elective lower segment caesarean section. There are several case reports in the literature discussing the optimal anaesthetic technique. In the past there has not been an emphasis on aggressive and early potassium replacement. A target level to commence replacement of potassium at 4.0 mmol/L or less is proposed. Careful preoperative preparation, frequent perioperative monitoring and early potassium replacement resulted in no perioperative episodes of weakness in this case, in contrast with other case reports where potassium was either not monitored or not replaced early enough, resulting in postoperative attacks. Another factor to consider in hypokalaemic periodic paralysis is the avoidance of triggers, including certain medications. Misoprostol was used in this instance to avoid potential electrolyte derangements from other uterotonics.

摘要

一位 32 岁的多产妇,患有家族性低钾周期性瘫痪,接受选择性下段剖宫产术的脊髓麻醉。文献中有几例病例报告讨论了最佳麻醉技术。过去,人们并没有强调积极和早期的钾替代。目前提出了一个目标值,即当血钾水平降至 4.0mmol/L 或更低时开始进行钾替代治疗。在这种情况下,通过仔细的术前准备、频繁的围手术期监测和早期的钾替代治疗,没有出现围手术期肌无力的情况,与其他病例报告形成对比,其中一些病例报告中没有监测钾水平,或者没有及时进行钾替代治疗,导致术后出现肌无力发作。低钾周期性瘫痪需要考虑的另一个因素是避免触发因素,包括某些药物。在这种情况下,使用米索前列醇是为了避免其他缩宫素引起的潜在电解质紊乱。

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