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婴儿自闭症的遗传学方面

Genetic aspects of infantile autism.

作者信息

Folstein S E

出版信息

Annu Rev Med. 1985;36:415-9. doi: 10.1146/annurev.me.36.020185.002215.

DOI:10.1146/annurev.me.36.020185.002215
PMID:3888060
Abstract

Infantile autism probably has many etiologies. Several specific genetic disorders appear to be associated with the syndrome much more often than would be expected by chance, but these account for only a minority of cases. In the majority of cases, where etiology is still unknown, genetic factors probably also play a role. Evidence suggests, however, that it is not autism per se that is inherited, but less severe abnormalities of language and cognition, which in turn lead to a predisposition to the development of autism in infants.

摘要

婴儿自闭症可能有多种病因。几种特定的遗传疾病似乎比偶然预期的更常与该综合征相关,但这些仅占少数病例。在大多数病因仍不明的病例中,遗传因素可能也起作用。然而,有证据表明,遗传的并非自闭症本身,而是不太严重的语言和认知异常,进而导致婴儿患自闭症的易感性。

相似文献

1
Genetic aspects of infantile autism.婴儿自闭症的遗传学方面
Annu Rev Med. 1985;36:415-9. doi: 10.1146/annurev.me.36.020185.002215.
2
Autism: familial aggregation and genetic implications.自闭症:家族聚集性及其遗传学意义
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[Twins with autism and mental retardation associated with balanced (7;20) chromosomal translocation].[患有自闭症和智力障碍且与平衡型(7;20)染色体易位相关的双胞胎]
Rev Chil Pediatr. 1986 Nov-Dec;57(6):549-54.
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Infantile autism in twins.
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[Genetic aspects of infantile autism].
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Neuropsychological functioning of siblings of children with autism, siblings of children with developmental language delay, and siblings of children with mental retardation of unknown genetic etiology.自闭症儿童的兄弟姐妹、发育性语言迟缓儿童的兄弟姐妹以及不明遗传病因的智力障碍儿童的兄弟姐妹的神经心理功能。
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引用本文的文献

1
Evolution in the Understanding of Autism Spectrum Disorder: Historical Perspective.对自闭症谱系障碍认识的演变:历史视角
Indian J Pediatr. 2017 Jan;84(1):44-52. doi: 10.1007/s12098-016-2080-8. Epub 2016 Apr 7.
2
Classification of autism and related conditions: progress, challenges, and opportunities.自闭症及相关病症的分类:进展、挑战与机遇
Dialogues Clin Neurosci. 2012 Sep;14(3):229-37. doi: 10.31887/DCNS.2012.14.3/fvolkmar.