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印度特里普拉邦南区一个村庄爆发水源性急性腹泻病:印度东北地区的公共卫生突发事件

Outbreak of waterborne acute diarrheal disease in a South District village of Tripura: A public health emergency in the Northeast region of India.

作者信息

Majumdar Tapan, Guha Hritusree, Tripura Amar, Sengupta Bitan, Ojha Anup Kumar, Das Samaresh, Chowdhury Goutam, Ramamurthy T, Das Madhuchhanda

机构信息

Department of Microbiology, Agartala Government Medical College, Tripura, India.

Department of Community Medicine, Agartala Government Medical College, Tripura, India.

出版信息

Heliyon. 2024 May 27;10(11):e31903. doi: 10.1016/j.heliyon.2024.e31903. eCollection 2024 Jun 15.

Abstract

Food and waterborne outbreaks are a neglected public health problem in India. However, it is important to identify the source of infection and the causative pathogen to curb the outbreak quickly and minimize mortality and morbidity. A retrospective descriptive study was conducted with a line list of 130 diarrheal cases. Epidemiological investigation and laboratory investigation were done. Data were collected from hospital case report forms as well as interviewed affected cases. A case of acute diarrheal disease was reported among the people in the village with abdominal pain, vomiting, and diarrhea from December 31, 2022 to January 3, 2023. Out of a total of 130 recorded cases, 33 stool samples were collected and were positive for Enteroaggregative , 3a, and by cultural and molecular tests. The presumptive fecal pollution indicator assay indicated high coliform counts in the water samples (most probable number [MPN]-05) and the presence of . The identified pathogens showed susceptibility to gentamicin and meropenem. People who used public drinking water were found to be infected with acute diarrheal disease (ADD). Quick identification of the causative pathogens and their antimicrobial resistance pattern helped correct antibiotic prescriptions and quick recovery of the patients without any deaths. Thus, a timely implementation of food and waterborne outbreak investigation is crucial to saving lives and preventing the spread of infection.

摘要

食源性和水源性疾病暴发在印度是一个被忽视的公共卫生问题。然而,识别感染源和致病病原体对于迅速控制疫情、降低死亡率和发病率至关重要。我们对130例腹泻病例的一览表进行了一项回顾性描述性研究。开展了流行病学调查和实验室调查。数据收集自医院病例报告表以及对受影响病例的访谈。2022年12月31日至2023年1月3日期间,该村村民中报告了一例伴有腹痛、呕吐和腹泻的急性腹泻病病例。在总共记录的130例病例中,收集了33份粪便样本,经培养和分子检测,这些样本对聚集性大肠杆菌、3a型以及[此处原文可能缺失部分信息]呈阳性。推测性粪便污染指标检测表明水样中大肠菌群数很高(最大可能数[MPN] - 05)且存在[此处原文可能缺失部分信息]。鉴定出的病原体对庆大霉素和美罗培南敏感。发现使用公共饮用水的人感染了急性腹泻病(ADD)。快速识别致病病原体及其抗菌耐药模式有助于正确开具抗生素处方,使患者迅速康复且无死亡病例。因此,及时开展食源性和水源性疾病暴发调查对于挽救生命和防止感染传播至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d992/11176748/9eb286a2b54b/gr1.jpg

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