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一例与全身性癫痫相关的频繁眨眼和眼球运动异常病例。

A Case of Frequent Blinking and Abnormal Eyeball Movement Associated with Generalized Epilepsy.

作者信息

Okudo Adaora C, Babalola Olufemi E, Ani-Osheku Ifeyinwa

机构信息

Rachel Eye Center, Abuja, Nigeria.

Department of Ophthalmology, Asokoro District Hospital, Abuja, Nigeria.

出版信息

Niger Med J. 2023 Feb 24;63(6):480-484. eCollection 2022 Nov-Dec.

Abstract

Eyelid myoclonus is an idiopathic generalized epileptic syndrome that can occur with or without absence seizures. The features include frequent blinking, an upward roll of the eyeballs, and slight backward movement of the head. It can be spontaneous or stimulated by light. Light and eyelid closure are triggers to the seizures. A 13-year-old young male student presented with a four months history of frequent blinking and abnormal eye movements. There was a positive history of leg tapping while asleep which started a year prior to presentation, but there was no loss of consciousness. On presentation, the patient was a young healthy looking myope who frequently blinks with sudden upward and left jerky movements of the eyeballs. Visual acuity was CF at 2 meters in both eyes improving with -4.50DS to 6/6. Intraocular pressures were 12 mmHg bilaterally. Anterior and posterior segment findings were normal. Brain MRI was normal, but EEG was abnormal with features suggestive of generalized epilepsy. He was co-managed with the neurologist and placed initially on Tabs Sodium valproate 250mg for 3 months. This was modified to Tabs Sodium Valproate (controlled release) 500mg at night since there was little change. This resulted in an appreciable reduction in blinking and abnormal eye movement. The leg tapping stopped on this dose. Eyelid myoclonus (EM) is a rare form of epilepsy. It is of utmost importance to create awareness of the disease among physicians. Early diagnosis and treatment are important prognostic factors of the disease. There is a need to create awareness of Eyelid Myoclonus among physicians as this can easily be missed or misdiagnosed.

摘要

眼睑肌阵挛是一种特发性全身性癫痫综合征,可伴有或不伴有失神发作。其特征包括频繁眨眼、眼球向上转动以及头部轻微向后移动。它可以是自发的,也可由光刺激诱发。光和眼睑闭合是发作的触发因素。一名13岁的年轻男学生有4个月频繁眨眼和异常眼球运动的病史。有睡眠时腿部敲击的阳性病史,该症状在就诊前一年开始出现,但无意识丧失。就诊时,患者是一名看起来健康的年轻近视者,频繁眨眼,眼球突然向上和向左急促运动。双眼视力在2米处为眼前指数,佩戴-4.50DS镜片后视力提高到6/6。双眼眼压均为12 mmHg。眼前段和眼后段检查结果正常。脑部磁共振成像正常,但脑电图异常,提示全身性癫痫。他由神经科医生共同管理,最初服用丙戊酸钠片250mg,持续3个月。由于变化不大,改为每晚服用丙戊酸钠(缓释)片500mg。这使得眨眼和异常眼球运动明显减少。服用该剂量后腿部敲击症状停止。眼睑肌阵挛(EM)是一种罕见的癫痫形式。在医生中提高对该疾病的认识至关重要。早期诊断和治疗是该疾病重要的预后因素。有必要在医生中提高对眼睑肌阵挛的认识,因为这种疾病很容易被漏诊或误诊。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f2c/11170254/d7636df5989d/nmj-63-480-f1.jpg

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本文引用的文献

1
Case Report: A Case of Eyelid Myoclonic Status With Tonic-Clonic Seizure and Literature Review.
Front Pediatr. 2021 Apr 22;9:671732. doi: 10.3389/fped.2021.671732. eCollection 2021.
2
Prognosis of Juvenile myoclonic epilepsy with eye-closure sensitivity.
Seizure. 2018 Nov;62:17-25. doi: 10.1016/j.seizure.2018.09.006. Epub 2018 Sep 17.
3
The New Classification of Seizures by the International League Against Epilepsy 2017.
Curr Neurol Neurosci Rep. 2017 Jun;17(6):48. doi: 10.1007/s11910-017-0758-6.
5
Status epilepticus in adults.
Lancet Neurol. 2015 Jun;14(6):615-24. doi: 10.1016/S1474-4422(15)00042-3. Epub 2015 Apr 20.
6
Jeavons syndrome in China.
Epilepsy Behav. 2014 Mar;32:64-71. doi: 10.1016/j.yebeh.2013.12.016. Epub 2014 Feb 1.
7
Jeavons syndrome existing as occipital cortex initiating generalized epilepsy.
Epilepsia. 2011 Jul;52(7):1273-9. doi: 10.1111/j.1528-1167.2011.03068.x. Epub 2011 Apr 19.
8
Myoclonic encephalopathy of infants.
J Neurol Neurosurg Psychiatry. 1962 Aug;25(3):271-6. doi: 10.1136/jnnp.25.3.271.
9
Sodium valproate: monotherapy and polytherapy.
Epilepsia. 1982 Dec;23(6):693-720. doi: 10.1111/j.1528-1157.1982.tb05085.x.

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